Reporting of health equity considerations in cluster and individually randomized trials

Simple item page
dc.contributor.authorPetkovic, Jenniferen_ZA
dc.contributor.authorJull, Janeten_ZA
dc.contributor.authorYoganathan, Manosilaen_ZA
dc.contributor.authorDewidar, Omaren_ZA
dc.contributor.authorBaird, Sarahen_ZA
dc.contributor.authorGrimshaw, Jeremy M.en_ZA
dc.contributor.authorJohansson, Kjell A.en_ZA
dc.contributor.authorKristjansson, Elizabethen_ZA
dc.contributor.authorMcGowan, Jessieen_ZA
dc.contributor.authorMoher, Daviden_ZA
dc.contributor.authorPetticrew, Marken_ZA
dc.contributor.authorRobberstad, Bjarneen_ZA
dc.contributor.authorShea, Beverleyen_ZA
dc.contributor.authorTugwell, Peter
dc.contributor.authorVolmink, Jimmyen_ZA
dc.contributor.authorWells, George A.en_ZA
dc.contributor.authorWhitehead, Margareten_ZA
dc.contributor.authorCuervo, Luis G.en_ZA
dc.contributor.authorWhite, Howarden_ZA
dc.contributor.authorTaljaard, Monicaen_ZA
dc.contributor.authorWelch, Vivianen_ZA
dc.date.accessioned2020-06-02T08:38:04Z
dc.date.available2020-06-02T08:38:04Z
dc.date.issued2020-04-03
dc.date.updated2020-04-05T03:15:28Z
dc.descriptionCITATION: Petkovic, J., et al. 2020. Reporting of health equity considerations in cluster and individually randomized trials. Trials, 21:308, doi:10.1186/s13063-020-4223-5.
dc.descriptionThe original publication is available at https://trialsjournal.biomedcentral.com
dc.description.abstractBackground: The randomized controlled trial (RCT) is considered the gold standard study design to inform decisions about the effectiveness of interventions. However, a common limitation is inadequate reporting of the applicability of the intervention and trial results for people who are “socially disadvantaged” and this can affect policy-makers’ decisions. We previously developed a framework for identifying health-equity-relevant trials, along with a reporting guideline for transparent reporting. In this study, we provide a descriptive assessment of healthequity considerations in 200 randomly sampled equity-relevant trials. Methods: We developed a search strategy to identify health-equity-relevant trials published between 2013 and 2015. We randomly sorted the 4316 records identified by the search and screened studies until 100 individually randomized (RCTs) and 100 cluster randomized controlled trials (CRTs) were identified. We developed and pilottested a data extraction form based on our initial work, to inform the development of our reporting guideline for equity-relevant randomized trials. Results: In total, 39 trials (20%) were conducted in a low- and middle-income country and 157 trials (79%) in a high-income country focused on socially disadvantaged populations (78% CRTs, 79% RCTs). Seventy-four trials (37%) reported a subgroup analysis across a population characteristic associated with disadvantage (25% CRT, 49% RCTs), with 19% of included studies reporting subgroup analyses across sex, 9% across race/ethnicity/culture, and 4% across socioeconomic status. No subgroup analyses were reported for place of residence, occupation, religion, education, or social capital. One hundred and forty-one trials (71%) discussed the applicability of their results to one or more socially disadvantaged populations (68% of CRT, 73% of RCT). Discussion: In this set of trials, selected for their relevance to health equity, data that were disaggregated for socially disadvantaged populations were rarely reported. We found that even when the data are available, opportunities to analyze health-equity considerations are frequently missed. The recently published equity extension of the Consolidated Reporting Standards for Randomized Trials (CONSORT-Equity) may help improve delineation of hypotheses related to socially disadvantaged populations, and transparency and completeness of reporting of health-equity considerations in RCTs. This study can serve as a baseline assessment of the reporting of equity considerations.en
dc.description.urihttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-020-4223-5
dc.description.versionPublisher's version
dc.format.extent12 pages ; illustrations
dc.identifier.citationPetkovic, J., et al. 2020. Reporting of health equity considerations in cluster and individually randomized trials. Trials, 21:308, doi:10.1186/s13063-020-4223-5
dc.identifier.issn1745-6215 (online)
dc.identifier.otherdoi:10.1186/s13063-020-4223-5
dc.identifier.urihttp://hdl.handle.net/10019.1/108624
dc.language.isoen_ZAen_ZA
dc.publisherBMC (part of Springer Nature)
dc.rights.holderAuthors retain copyright
dc.subjectHealth services accessibilityen_ZA
dc.subjectMedical care -- Supply and demanden_ZA
dc.subjectClinical trialsen_ZA
dc.titleReporting of health equity considerations in cluster and individually randomized trialsen_ZA
dc.typeArticle
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
petkovic_reporting_2020.pdf
Size:
829.88 KB
Format:
Adobe Portable Document Format
Description:
Download article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
0 B
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Research Articles (Health Sciences)