Investigation and management of primary immunodeficiency in South African children
Date
2014
Journal Title
Journal ISSN
Volume Title
Publisher
Health and Medical Publishing Group
Abstract
ENGLISH ABSTRACT: The primary immunodeficiency diseases (PIDs) are inherited, non-communicable diseases that cause immunological dysfunction. PIDs are seldom reported in South Africa (SA). Based on a mid-2013 population estimate of 52.98 million and assuming that the prevalence of PIDs is similar to that in well-resourced settings, the total number of individuals with PIDs in our country should range between 2 850 and 45 723. However, fewer than 500 cases of PID have been reported in SA. Between five and 15 new, fully characterised PIDs are reported annually. Our understanding of the physiology of the immune system has been substantially enhanced by these discoveries, and consequently the international classification of PIDs has been updated.
Description
CITATION: Eley, B. & Esser, M. 2014. Investigation and management of primary immunodeficiency in South African children. South African Medical Journal, 104(11): 793-796, doi: 10.7196/SAMJ.8946.
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Primary immunodeficiency -- Children, Immune deficiency -- Investigation, Immune deficiency -- Management
Citation
Eley, B. & Esser, M. 2014. Investigation and management of primary immunodeficiency in South African children. South African Medical Journal, 104(11): 793-796, doi: 10.7196/SAMJ.8946