ITEM VIEW

Nephroblastoma - a 25 year review of a South African unit

dc.contributor.authorVisser, Yolandi Thelmaen_ZA
dc.contributor.authorUys, Ronelleen_ZA
dc.contributor.authorVan Zyl, Anelen_ZA
dc.contributor.authorStefan, Daniela Cristinaen_ZA
dc.date.accessioned2015-05-20T09:12:35Z
dc.date.available2015-05-20T09:12:35Z
dc.date.issued2014-09-15en
dc.identifier.citationVisser, Y. T., et al. 2014. Nephroblastoma - a 25 year review of a South African unit. Journal of medicine and life, 7(3):445–449
dc.identifier.issn1844-3117 (online)
dc.identifier.issn1844-122X (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/96589
dc.descriptionCITATION: Visser, Y. T., et al. 2014. Nephroblastoma - a 25 year review of a South African unit. Journal of medicine and life, 7(3):445–449.
dc.descriptionThe original publication is available at http://www.medandlife.ro/
dc.description.abstractRationale: To determine the outcome of patients with nephroblastoma in a South African hospital. Objective: To determine if there is a difference in the outcome of patients with nephroblastoma comparing two treatment protocols SIOP (Société International D’Oncologie Pédiatrique Protocol) versus NWTS (National Wilms’ Tumour Study Protocol). Methods and results: A retrospective audit of 25 years (1983-2007), of children diagnosed with nephroblastoma in Tygerberg Hospital. One hundred and seven patients were included in the study and 98 were analyzed. The average age at diagnosis was 3.8 years. Most patients (37%) presented with stage 1 of the disease, followed by patients with stage 3 (27%). Most patients were treated according to the SIOP protocol (61%). Gender and race did not influence the outcome. Patients with stage 1 and 2 of the disease had the best outcome (76% versus 43% for stages 3 and 4). The SIOP group had a better outcome than the NWTS group (p value 0.001). The two groups had an equal distribution of the stage of presentation. The tumor volumes were bigger in the NWTS group (1004cm3 compared to 613cm3). Nutritional status did not influence the outcome although more patients were underweight for age in the SIOP group. The statistical methods used were: Kaplan Meier, Gehan’s Wilcoxon Test, Chi –square test and the Fisher exact test.en_ZA
dc.description.urihttp://www.medandlife.ro/archive/31-vol-vii-iss-3-july-september-2014/special-articles/74-nephroblastoma-a-25-year-review-of-a-south-african-unit
dc.format.extent11 pages
dc.language.isoen_ZAen_ZA
dc.publisherPubMed Central
dc.subjectNephroblastomaen_ZA
dc.subjectCancer in children -- Treatment -- South Africaen_ZA
dc.subjectTumors in children -- Treatment -- South Africaen_ZA
dc.subjectTygerberg Children's Hospitalen_ZA
dc.titleNephroblastoma - a 25 year review of a South African uniten_ZA
dc.typeArticleen_ZA
dc.description.versionPost print
dc.rights.holderJournal of medicine and life


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

ITEM VIEW