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Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls

dc.contributor.authorMatsha, Tandi E.en_ZA
dc.contributor.authorKengne, Andre-Pascalen_ZA
dc.contributor.authorYako, Yandiswa Y.en_ZA
dc.contributor.authorHon, Gloudina M.en_ZA
dc.contributor.authorHassan, Mogamat S.en_ZA
dc.contributor.authorErasmus, Rajiv T.en_ZA
dc.date.accessioned2014-07-07T12:12:42Z
dc.date.available2014-07-07T12:12:42Z
dc.date.issued2013-08-13
dc.identifier.citationMatsha, T. E. et al. 2013. Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls. PLoS ONE, 8(8): e71133, doi:10.1371/journal.pone.0071133.
dc.identifier.issn1932-6203 (online)
dc.identifier.otherdoi:10.1371/journal.pone.0071133
dc.identifier.urihttp://hdl.handle.net/10019.1/92125
dc.descriptionCITATION: Matsha, T. E. et al. 2013. Optimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girls. PLoS ONE, 8(8): e71133, doi:10.1371/journal.pone.0071133.
dc.descriptionThe original publication is available at http://journals.plos.org/plosone
dc.description.abstractBackground The proposed waist-to-height ratio (WHtR) cut-off of 0.5 is less optimal for cardiometabolic risk screening in children in many settings. The purpose of this study was to determine the optimal WHtR for children from South Africa, and investigate variations by gender, ethnicity and residence in the achieved value. Methods Metabolic syndrome (MetS) components were measured in 1272 randomly selected learners, aged 10–16 years, comprising of 446 black Africans, 696 mixed-ancestry and 130 Caucasians. The Youden’s index and the closest-top-left (CTL) point approaches were used to derive WHtR cut-offs for diagnosing any two MetS components, excluding the waist circumference. Results The two approaches yielded similar cut-off in girls, 0.465 (sensitivity 50.0, specificity 69.5), but two different values in boys, 0.455 (42.9, 88.4) and 0.425 (60.3, 67.7) based on the Youden’s index and the CTL point, respectively. Furthermore, WHtR cut-off values derived differed substantially amongst the regions and ethnic groups investigated, whereby the highest cut-off was observed in semi-rural and white children, respectively, Youden’s index0.505 (31.6, 87.1) and CTL point 0.475 (44.4, 75.9). Conclusion The WHtR cut-off of 0.5 is less accurate for screening cardiovascular risk in South African children. The optimal value in this setting is likely gender and ethnicity-specific and sensitive to urbanization.en_ZA
dc.description.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0071133
dc.format.extent7 pages
dc.language.isoen
dc.publisherPLoS
dc.subjectWaist-to-height ratioen_ZA
dc.subjectChildren -- Medical screening -- South Africaen_ZA
dc.subjectHeart -- Diseases -- Risk factorsen_ZA
dc.subjectMetabolic syndromeen_ZA
dc.titleOptimal waist-to-height ratio values for cardiometabolic risk screening in an ethnically diverse sample of South African urban and rural school boys and girlsen_ZA
dc.typeArticle
dc.description.versionPublisher's version
dc.rights.holderAuthors retain copyright


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