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Laboratory tests in the diagnosis of cystic fibrosis

Hoffmann, M. ; Meyer, W. P. (2012-07)

Please cite as follows: Hoffmann, M. & Meyer, W. P. 2012. Laboratory tests in the diagnosis of cystic fibrosis. CME Journal, 30(7):256-257.

The original publication is available at


Cystic fibrosis (CF) is the most common autosomal recessive disorder among white individuals, and occurs in all South African population groups. Recent evidence suggests a prevalence of 1 in 2 000 among white South Africans and 1 in 12 000 in the coloured population. In black South Africans carrier frequency estimates have been used to project the incidence of 1 in 4 624 live births. Generally, South Africa offers diagnostic services and expertise similar to those available worldwide for CF patients.

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