Neonatal pancreatic function in infants born to mothers with gestational and overt diabetes

De Villiers, T. J. ; MacFarlane, C. M. ; Tsakalakos, N. ; Taljaard, J. J. F. (1984-11)

The original publication is available at http://www.samj.org.za

Article

Neonatal pancreatic function was assessed in infants born to non-diabetic mothers and to mothers with well-controlled gestational diabetes (GD) and overt diabetes (OD) using cord blood C-peptide estimations and the calculation of cord C-peptide/glucose ratios. Exaggerated pancreatic function was present in infants born to mothers with GD. In these infants the increased cord C-peptide values and cord C-peptide/glucose ratios correlated with their increased birth weight ratios. These results could not be explained on the basis of maternal hyperglycaemia and a possible intrinsic difference in pancreatic response between infants born to mothers with GD and those born to mothers with OD is suggested.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/8021
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