Flunisolide nasal spray in the treatment of perennial rhinitis
The original publication is available at http://www.samj.org.za
Twenty patients with perennial rhinitis took part in a double-blind, randomized, cross-over comparison of flunisolide nasal spray (Syntaris; Syntex) and its vehicle. The sprays were used twice daily for 4 weeks and a total daily dose of 200 μg flunisolide was used. Flunisolide was superior to the placebo in relieving sneezing, runny nose and nose-blowing (P < 0.05). Patient and doctor treatment preferences were significantly in favour of the active spray. Side-effects were mainly confirmed to nasal irritation and occurred equally in both treatment groups.
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