Sodium valproate poisoning. A case report

Van der Merwe, A.C. ; Albrecht, C.F. ; Brink, M.S. ; Coetzee, A.R. (1985)

CITATION: Van der Merwe, A. C. et al. 1985. Sodium valproate poisoning. A case report. South African Medical Journal, 67:735-736.

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A case of a severe overdose of sodium valproate (more than 10 times the therapeutic requirement) is discussed. The patient presented with central nervous, respiratory and cardiovascular depression and was treated with supportive therapy and haemoperfusion. However, on available data it would appear that haemoperfusion did not make a significant contribution towards the patient's recovery.

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