The relative biological effectiveness of 100 kV X-rays determined by the V-79 cell colony assay

Winzel E. ; Van Der Merwe E.J. ; Groenewald W. (1987)

Article

The original publication is available at http://www.samj.org.za

Article

The relative biological effectiveness (RBE) of 100 kV X-rays compared with cobalt-60-γ-irradiation was determined using a cell colony assay based on the survival of Chinese hamster V-79 lung fibroblasts. The 37% dose (D(o)) was found to range from 1.12 to 1.47 and from 1.33 to 1.63 Gy for X-rays and 60Co-γ-irradiation respectively. The mean RBE value calculated from the D(o) values was found to be 1.13 ± 0.04. This figure compares favourably with RBE values calculated from D(o) values using other endpoints.

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