Tuberculosis and phrenic nerve destruction

dc.contributor.authorDempers, Johan J.
dc.contributor.authorBezuidenhout, Juanita
dc.contributor.authorSchneider, Johann W.
dc.contributor.authorJanse van Rensburg, Michèle
dc.identifier.citationDempers, JJ, Bezuidenhout, J, Schneider, JW & Janse van Rensburg, M 2007, 'Tuberculosis and phrenic nerve destruction', SAMJ, vol. 97, no. 8, pp. 573-573.en_ZA
dc.identifier.issn0256-9574 (print)
dc.identifier.issn2078-5135 (online)
dc.description.abstractENGLISH ABSTRACT: Phrenic nerve palsy (PNP) is often associated with Mycobacterium tuberculosis-related expansile pneumonia, possibly because of nerve entrapment by healing fibrosis. Mohan and Jayaswal1 postulated that pressure on the left phrenic nerve by an enlarged hilar lymph node caused unilateral diaphragmatic paralysis in a 6-year-old boy who developed PNP during the course of pulmonary tuberculosis (PTB). Gie et al. described 6 childhood cases of PTB complicated by unilateral PNP. The children did not recover on antituberculosis drugs and steroids, or in 1 case, after surgical decompression. Therefore the theory of glandular compression alone does not adequately account for PNP as a complication of PTB. Our case, in which the fate of the phrenic nerve was confirmed, provides strong evidence that destruction of the phrenic nerve by the tuberculous inflammatory process is involved in the pathogenesis of diaphragmatic paralysis, which may influence the clinical management of these children.en_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)en_ZA
dc.subjectPhrenic nerve palsyen_ZA
dc.subjectPhrenic nerve destructionen_ZA
dc.subject.lcshPhrenic nerve
dc.titleTuberculosis and phrenic nerve destructionen_ZA

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