Tuberculosis and phrenic nerve destruction

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Show simple item record Dempers, Johan J. Bezuidenhout, Juanita Schneider, Johann W. Janse van Rensburg, Michèle 2010-06-17T13:16:40Z 2010-06-17T13:16:40Z 2007-08
dc.identifier.citation Dempers, JJ, Bezuidenhout, J, Schneider, JW & Janse van Rensburg, M 2007, 'Tuberculosis and phrenic nerve destruction', SAMJ, vol. 97, no. 8, pp. 573-573. en_ZA
dc.identifier.issn 0256-9574 (print)
dc.identifier.issn 2078-5135 (online)
dc.description.abstract ENGLISH ABSTRACT: Phrenic nerve palsy (PNP) is often associated with Mycobacterium tuberculosis-related expansile pneumonia, possibly because of nerve entrapment by healing fibrosis. Mohan and Jayaswal1 postulated that pressure on the left phrenic nerve by an enlarged hilar lymph node caused unilateral diaphragmatic paralysis in a 6-year-old boy who developed PNP during the course of pulmonary tuberculosis (PTB). Gie et al. described 6 childhood cases of PTB complicated by unilateral PNP. The children did not recover on antituberculosis drugs and steroids, or in 1 case, after surgical decompression. Therefore the theory of glandular compression alone does not adequately account for PNP as a complication of PTB. Our case, in which the fate of the phrenic nerve was confirmed, provides strong evidence that destruction of the phrenic nerve by the tuberculous inflammatory process is involved in the pathogenesis of diaphragmatic paralysis, which may influence the clinical management of these children. en_ZA
dc.language.iso en_ZA en_ZA
dc.publisher Health and Medical Publishing Group (HMPG) en_ZA
dc.subject Phrenic nerve palsy en_ZA
dc.subject PNP en_ZA
dc.subject Tuberculosis en_ZA
dc.subject Phrenic nerve destruction en_ZA
dc.subject.lcsh Phrenic nerve
dc.title Tuberculosis and phrenic nerve destruction en_ZA
dc.type Article en_ZA
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