Creatine and exercise – strong evidence for stronger heart muscle

Webster, Ingrid ; Huisamen, Barbara ; Du Toit, Eugene F. (2011-10)

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Publication of this article was funded by the Stellenbosch University Open Access Fund.



There has been a dramatic increase in the use of dietary creatine supplementation among sports men and women, and by clinicians as a therapeutic agent in muscular and neurological diseases. The effects on skeletal muscles have been documented and reviewed extensively. However, this review looks at another important muscle – the heart – and both the advantages and disadvantages to creatine supplementation, exercise, and the combination. The proposed mechanisms of each are examined and explained.

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