Objectives: Structural magnetic resonance imaging (sMRI) studies of anxiety disorders in children and adolescents are limited. Posttraumatic stress disorder (PTSD) and obsessive compulsive disorder (OCD) have been best ...
Malan-Muller, StefanieHemmings, Sian M. J.Spies, GeorginaKidd, MartinFennema-Notestine, ChristineSeedat, Soraya(PLoS, 2013-03)
The neuropathogenesis of the human immunodeficiency virus (HIV) may manifest as various neurocognitive impairments (NCI). HIV-positive individuals also have significantly shorter telomere length (TL) in peripheral blood ...
Malan-Muller, StephanieHemmings, Sian Megan JoannaSeedat, Soraya(SpringerLink, 2012-11)
Epigenetic and regulatory elements provide an
additional layer of complexity to the heterogeneity of anxiety
disorders. MicroRNAs (miRNAs) are a class of small,
noncoding RNAs that have recently drawn interest as ...
Background
Multiple relapses characterise the course of illness in most patients with schizophrenia, yet
the nature of these episodes has not been extensively researched and clinicians may not
always be aware of important ...
Background Exposure to early adverse events can result in the development of later psychopathology, and is often associated with cognitive impairment. This may be due to accelerated cell aging, which can be catalogued by ...
ENGLISH ABSTRACT: HIV infection, substance abuse, and psychiatric disorders are major public health
issues in South Africa. Psychiatric disorders and substance-use disorders together
have a negative impact on the health ...
Background: High rates of childhood maltreatment have been documented in HIV-positive men and women. In addition, mental disorders are highly prevalent in both HIV-infected individuals and victims of childhood maltreatment. ...
Botha, Ulla A.Koen, LiezlJoska, John A.Hering, Linda M.Oosthuizen, Piet P.(BioMed Central, 2010-09)
Background: A number of recently published randomized controlled trials conducted in developed countries have
reported no advantage for assertive interventions over standard care models. One possible explanation could ...
Carey, Paul D. (Paul Dermot)(Stellenbosch : Stellenbosch University, 2008-03)
ENGLISH ABSTRACT: Investigations into the neurobiology of obsessive-compulsive disorder (OCD) have provided useful insights into this prevalent and disabling disorder in recent decades. Encouraging advances have also been ...
ENGLISH ABSTRACT: The overall aim of these studies was to investigate selected aspects of psychopathology,
neurobiological abnormalities and treatment in schizophrenia.
The following topics were researched:
1. ...
Troeman, Zyrhea C. E.Spies, GeorginaCherner, MarianaArchibald, Sarah L.Fennema-Notestine, ChristineTheilmann, Rebecca J.Spottiswoode, BruceStein, Dan J.Seedat, Soraya(BioMed Central, 2011- 09)
Background While there are many published studies on HIV and functional limitations, there are few in the context of early abuse and its impact on functionality and Quality of Life (QoL) in HIV. Methods The present study ...
Ferrett, Helen Louise(Stellenbosch : Stellenbosch University, 2011-12)
ENGLISH ABSTRACT: The practice of psychometric testing of cognitive functioning in South Africa is hampered by
the paucity of normative data that adequately characterize our ethnically, linguistically,
socioeconomically, ...
ENGLISH ABSTRACT: It is well established that South African women are disproportionately affected by
HIV/AIDS and gender based violence. Research to date has provided evidence for
neurocognitive decline in individuals ...
Chishinga, NathanielKinyanda, EugeneWeiss, Helen A.Patel, VikramAyles, HelenSeedat, Soraya(BioMed Central, 2011-05-04)
This study was conducted to evaluate the diagnostic accuracy and determine the optimum cut-off scores for clinical use of the Center for Epidemiological Studies Depression scale (CES-D) and Alcohol Use Disorders Identification ...
The indications for termination of pregnancy in terms of the Abortion and Sterilization Act of 1975, and the evaluation of 100 pregnant White women are discussed.