Department of Psychiatry
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The relationship between potentially traumatic or stressful events, HIV infection and neurocognitive impairment (NCI) : a systematic review of observational epidemiological studies
(Taylor & Francis, 2020)Background: HIV/AIDS and potentially traumatic events (PTEs) or stressful life events (SLEs) and/or PTSD are independently associated with neurocognitive impairment (NCI). Literature suggests that HIV and PTE/SLE exposure ... -
Correction to: Evaluating a screener to quantify PTSD risk using emergency care information : a proof of concept study
(BMC (part of Springer Nature), 2020-06-29)An amendment to this paper has been published and can be accessed via the original article. -
Safety of psychotropic medications in people with COVID-19 : evidence review and practical recommendations
(BMC (part of Springer Nature), 2020-07-15)Background: The novel coronavirus pandemic calls for a rapid adaptation of conventional medical practices to meet the evolving needs of such vulnerable patients. People with coronavirus disease (COVID-19) may frequently require ... -
Distant mood monitoring for depressive and bipolar disorders : a systematic review
(BMC (part of Springer Nature), 2020-07-22)Background: Broadening our knowledge of the longitudinal course of mood symptoms is cardinal to providing effective long-term treatments. Research indicates that patients with mental illness are willing to engage in the ... -
Impact of child emotional and behavioural difficulties on educational outcomes of primary school children in Ethiopia : a population-based cohort study
(BMC (part of Springer Nature), 2020-05-16)Background: The relationship between child emotional and behavioural difficulties (EBD) and educational outcomes has not been investigated in prospective, community studies from low-income countries. Methods: The association ... -
Does higher severity really correlate with a worse quality of life in obsessive compulsive disorder? A meta-regression
(Dove Medical Press, 2018)Background: Obsessive–compulsive disorder (OCD) is one of the leading causes of disability and reduced quality of life (QOL), with impairment in a number of domains. However, there is a paucity of literature on the association ... -
HPA-axis genes as potential risk variants for neurocognitive decline in trauma-exposed, HIV-positive females
(Dove Medical Press, 2018)Purpose: Previous studies have independently provided evidence for the effects of HIV infection, hypothalamic–pituitary–adrenal (HPA) axis dysfunction and early life trauma on neurocognitive impairment (NCI). This study ... -
Efficacy and safety profile of paliperidone palmitate injections in the management of patients with schizophrenia : an evidence-based review
(Dove Medical Press, 2018)The course of schizophrenia is characterized by multiple relapses, incomplete remission of symptoms, enduring cognitive deficits, and social and occupational functional impairments. Nonadherence to antipsychotic medication ... -
Screening for consequences of trauma – an update on the global collaboration on traumatic stress
(Taylor & Francis, 2020)This letter provides an update on the activities of “The Global Collaboration on Traumatic Stress” (GC-TS) as first described by Schnyder et al. in 2017. It presents in further detail the projects of the first theme, in ... -
Methods of deliberate self-harm in a tertiary hospital in South Africa
(AOSIS, 2020)Background: Little is known about the methods of deliberate self-harm (DSH) in South Africa (SA), despite the importance of means restriction as a public health strategy to reduce the morbidity and mortality associated ... -
Prognostic value of motor timing in treatment outcome in patients with alcohol- and/or cocaine use disorder in a rehabilitation program
(Frontiers Media, 2018)Introduction: Individuals with Substance Use Disorder (SUD) often have cognitive deficits in multiple domains, including motor timing deficits, with recovery times of up to 1 year. Cognitive deficits influence treatment ... -
Neurological soft signs, spontaneous and treatment emergent extrapyramidal syndromes in Black Africans with first episode schizophrenia
(Frontiers Media, 2018)Background: Very little is known about the relationship between spontaneous and treatment-induced motor syndromes in Africans with first episode schizophrenia. Objective: We investigated the association between spontaneous ... -
Evaluating a screener to quantify PTSD risk using emergency care information : a proof of concept study
(BMC (part of Springer Nature), 2020-03-02)Background: Previous work has indicated that post-traumatic stress disorder (PTSD) symptoms, measured by the Clinician-Administered PTSD Scale (CAPS) within 60 days of trauma exposure, can reliably produce likelihood estimates ... -
Body dysmorphic disorder : a diagnostic challenge in adolescence
(AOSIS, 2018)Body dysmorphic disorder (BDD) is a chronic and disabling condition that is characterised by distressing preoccupations with perceived defects in one’s own appearance, which might be slight or not observable to others. It ... -
An investigation of the relationship between PTSD, reflective functioning and caregiving sensitivity amongst mothers misusing substances
(Stellenbosch : Stellenbosch University, 2020-03)ENGLISH SUMMARY : Substance use has increased significantly in South Africa and has been associated with several risk factors for both maternal and infant mental health including dysfunctional parenting practices. Trauma ... -
Toward identifying reproducible brain signatures of obsessive-compulsive profiles : rationale and methods for a new global initiative
(BMC (part of Springer Nature), 2020-02-14)Background: Obsessive-compulsive disorder (OCD) has a lifetime prevalence of 2–3% and is a leading cause of global disability. Brain circuit abnormalities in individuals with OCD have been identified, but important knowledge ... -
Prospective interepisodal mood monitoring in patients with affective disorders : a feasibility study
(Dove Medical Press, 2017)Objectives : Our primary objective was to assess the feasibility of interepisodal telephonic mood monitoring in patients with affective disorders in a low-resource setting. Secondary objectives included gathering data on ... -
Cultural considerations in the classification of mental disorders : why and how in ICD-11
(BMC (part of Springer Nature), 2020-01-27)No abstract available. -
The effect of childhood trauma, ApoE genotype and HIV-1 viral protein R variants on change in cognitive performance
(BMC (part of Springer Nature), 2019-12-27)Objective: Gene–environment interactions contribute to the development of HIV-associated neurocognitive disorders. We examined whether childhood trauma, apolipoprotein E isoforms and viral protein R (Vpr) variants were ... -
Tobacco use and nicotine dependence among people living with HIV who drink heavily in South Africa : a cross-sectional baseline study
(BMC (part of Springer Nature), 2019-12-16)Background: People living with HIV (PLWH) who drink alcohol and use tobacco are particularly vulnerable to tobacco-induced diseases due to an already compromised immune system. This study investigated the prevalence and ...
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