Department of Psychiatry
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Digit ratio as an endophenotype in a schizophrenia population
(AOSIS, 2021-03)Background: Schizophrenia is a debilitating mental health condition affecting the lives of many South Africans. The origins of the heterogeneity in the presentation of the illness remain uncertain. Aim: This cross-sectional ... -
Becoming a Xhosa traditional healer : the calling, illness, conflict and belonging
(AOSIS, 2021-03)Background: Traditional healers (THs) are an important part of the healthcare system in sub-Saharan Africa. Understanding their training, experiences of becoming healers and their perceived roles in society is critical. Aim: ... -
Associations of premorbid adjustment with type and timing of childhood trauma in first-episode schizophrenia spectrum disorders
(AOSIS, 2021-06)Background: Childhood trauma may contribute to poorer premorbid social and academic adjustment which may be a risk factor for schizophrenia. Aim: We explored the relationship between premorbid adjustment and childhood ... -
Inequality and mental healthcare utilisation among first-year university students in South Africa
(BMC, 2020-01-25)Background: Addressing inequalities in mental healthcare utilisation among university students is important for socio-political transformation, particularly in countries with a history of educational exclusion. Methods: ... -
“Moving forward with life” : acceptability of a brief alcohol reduction intervention for people receiving antiretroviral therapy in South Africa
(MDPI, 2020-08)Background: In South Africa, interventions are needed to address the impact of hazardous drinking on antiretroviral therapy among people living with HIV (PLWH). Participant feedback about these interventions can identify ... -
Characteristics and predictors of Heavy Episodic Drinking (HED) among young people aged 16–25 : the International Alcohol Control Study (IAC), Tshwane, South Africa
(MDPI, 2020-05)In South Africa, little is known about alcohol consumption patterns, such as drinks consumed, container size, salience of alcohol price, affordability and availability, and perceptions of alcohol policies as potential ... -
The prevalence of mental health problems in sub-Saharan adolescents living with HIV : a systematic review
(Cambridge University Press, 2020-09)Despite the progress made in HIV treatment and prevention, HIV remains a major cause of adolescent morbidity and mortality in sub-Saharan Africa. As perinatally infected children increasingly survive into adulthood, the ... -
Preventing problematic internet use during the COVID-19 pandemic : consensus guidance
(Elsevier Inc, 2020-07)As a response to the COVID-19 pandemic, many governments have introduced steps such as spatial distancing and "staying at home" to curb its spread and impact. The fear resulting from the disease, the 'lockdown' situation, ... -
Increase in HIV incidence in women exposed to rape
(Wolters Kluwer Health, 2021-03)Objective: To determine the incidence of HIV acquisition in women postrape compared with a cohort of women who had not been raped. Design: A prospective cohort study. Methods: The Rape Impact Cohort Evaluation study based ... -
Brain structural covariance networks in obsessive-compulsive disorder: a graph analysis from the ENIGMA Consortium
(2020-02)Brain structural covariance networks reflect covariation in morphology of different brain areas and are thought to reflect common trajectories in brain development and maturation. Large-scale investigation of structural ... -
Structural and functional brain network connectivity in prenatal alcohol exposed neonates as assessed by multimodal brain imaging
(2020)Prenatal alcohol exposure leads to alterations in cognition, behavior and underlying brain architecture. However, prior studies have not integrated structural and functional imaging data in children with prenatal alcohol ... -
The clinical course and outcomes of first episode psychosis : a study of the acute, medium and long-term outcomes in a cohort rigorously treated in the early phase of illness
(Stellenbosch : Stellenbosch University, 2022-04)ENGLISH SUMMARY: The period surrounding the first episode of psychosis represents a critical period in the natural course of the illness. There are several studies on the nature of the clinical presentation, the effects ... -
Problematic use of the internet and family functioning : a quantitative investigation
(Stellenbosch : Stellenbosch University, 2022-04)ENGLISH SUMMARY: The internet is intertwined with most aspects of our daily lives and contribute considerably to the progression of humankind. Nevertheless, the excessive and maladaptive use of the internet are linked to ... -
I know that it's something that's creating a bond : fathers' experiences of participating in baby theater with their infants in South Africa
(Frontiers Media, 2020)In many African countries, particularly those with largely patriarchal societies like South Africa, promoting father-child interaction can pose a challenge. An informative medium that could potentially encourage active ... -
Genome-wide differentially methylated genes associated with posttraumatic stress disorder and longitudinal change in methylation in rape survivors
(Springer Nature, 2019)ENGLISH ABSTRACT: Rape is associated with a high risk for posttraumatic stress disorder (PTSD). DNA methylation changes may confer risk or protection for PTSD following rape by regulating the expression of genes implicated ... -
Strategies to strengthen the provision of mental health care at the primary care setting : an evidence map
(Public Library of Science, 2019)In a deinstitutionalised mental health care system, those with mental illness require complex, multidisciplinary and intersectoral care at the primary or community service setting. This paper describes an Evidence Map of ... -
Host and microbiome genome-wide association studies : current state and challenges
(Frontiers Media, 2019)The involvement of the microbiome in health and disease is well established. Microbiome genome-wide association studies (mGWAS) are used to elucidate the interaction of host genetic variation with the microbiome. The ... -
Internalizing mental disorders and accelerated cellular aging among perinatally HIV-infected youth in Uganda
(Frontiers Media, 2019)Introduction: Internalizing mental disorders (IMDs) in HIV+ children and adolescents are associated with impaired quality of life and non-adherence to anti-retroviral treatment. Telomere length is a biomarker of cellular ... -
Assessing cognition in children with prenatal methamphetamine exposure in South Africa
(Elsevier, 2019)No abstract available. -
Electronic cigarettes : the solution or yet another phase of the tobacco epidemic?
(SAGE Publications, 2019)Tobacco use is the single largest preventable cause of death globally. For years, the tobacco industry sought to create a tobacco product that is less controversial than conventional cigarettes. Electronic cigarettes were ...