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  The prevalence of compassion fatigue and burnout among healthcare professionals in intensive care units : a systematic review 

  Van Mol, Margo M. C.; Kompanje, Erwin J. O.; Benoit, Dominique D.; Bakker, Jan; Nijkamp, Marjan D. (Public Library of Science, 2015)

  Background: Working in the stressful environment of the Intensive Care Unit (ICU) is an emotionally charged challenge that might affect the emotional stability of medical staff. The quality of care for ICU patients and ...
  
  
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  Doing their best : strategies used by South African clinicians in working with psychiatric inpatients across a language barrier 

  Kilian, Sanja; Swartz, Leslie; Chiliza, Bonginkosi (Co-Action Publishing, 2015-10-26)

  Background and objectives: South Africa has 11 official languages, but most psychiatrists can speak only English and Afrikaans and there are no formal interpreter posts in the mental healthcare system. As a result clinicians ...
  
  
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  Anger and Afrophobia in South Africa : what is a health practitioner to do? 

  Long, Wahbie; Chiliza, Bonga; Stein, Dan J. (Health and Medical Publishing Group, 2015)

  The facts seem to indicate that South Africa is one of the more violent places on earth. We have been, and continue to be, a country with significant levels of political violence, criminal violence and domestic violence. ...
  
  
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  Identifying perceived barriers to monitoring service quality among substance abuse treatment providers in South Africa 

  Myers, Bronwyn; Petersen, Zainonisa; Kader, Rehana; Koch, J. Randy; Manderscheid, Ron; Govender, Rajen; Parry, Charles D. H. (BioMed Central, 2014-02-05)

  Background: A performance measurement system is planned for South African substance abuse treatment services. Provider-level barriers to implementing these systems have been identified in the United States, but little ...
  
  
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  Kleine-Levin syndrome as a neuropsychiatric presentation : a case report and review 

  Lachman, Anusha (AOSIS Publishing, 2014-07-30)

  Kleine-Levin syndrome (KLS) is a rare disorder characterised by hypersomnia, hyperphagia and behavioural disturbances. It typically occurs in adolescent men and may mimic a variety of neuropsychiatric conditions. Here we ...
  
  
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  Undiagnosed metabolic syndrome and other adverse effects among clozapine users of Xhosa descent 

  Faasen, N.; Niehaus, Dana J. H.; Koen, L.; Jordaan, E. (AOSIS Publishing, 2014-07)

  Background. Clozapine use is known to be associated with significant side-effects, including prolongation of the QT-interval, agranulocytosis and metabolic syndrome. However, few data exist on the prevalence of clozapine ...
  
  
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  Staff and bed distribution in public sector mental health services in the Eastern Cape Province, South Africa 

  Sukeri, Kiran; Alonso-Betancourt, Orlando; Emsley, Robin (AOSIS Publishing, 2014-11)

  Background. The Eastern Cape Province of South Africa is a resource-limited province with a fragmented mental health service. Objective. To determine the current context of public sector mental health services in terms ...
  
  
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  The South African Society of Psychiatrists (SASOP) treatment guidelines for psychiatric disorders 

  Emsley, R.; Colin, F.; Flisher, A. J.; Grobler, G.; Hawkridge, S.; Potocnik, F. C.; Seedat, S.; Stein, D. J.; Swingler, D.; Szabo, C. P. (AOSIS Publishing, 2013-08)

  The South African Society of Psychiatrists (SASOP) Treatment Guidelines for Psychiatric Disorders have been developed in order to address the local need for guidelines in our unique clinical setting.
  
  
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  Outcomes of adult heroin users v. abstinent users four years after presenting for heroin detoxification treatment 

  Khan, Zureida; Cloete, Karen Jacqueline; Harvey, Justin; Weich, Lize (AOSIS Publishing, 2014-08)

  Background. There are no studies in South Africa (SA) on the outcomes following detoxification and psychosocial rehabilitation of heroindependent patients. Objective. To compare the demographic, clinical, forensic and ...
  
  
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  Management of mental health disorders and central nervous system sequelae in HIV-positive children and adolescents 

  Nassen, R.; Donald, K.; Walker, K.; Paruk, S.; Vujovic, M.; Duncan, W.; Laughton, B.; Moos, B.; Eley, B.; Lachman, A.; Wilmshurst, J. (AOSIS Publishing, 2014-09)

  HIV-positive children and adolescents are at increased risk of both central nervous system (CNS) sequelae and mental disorders owing to a number of factors, including the impact of HIV infection on the brain, social ...
  
  
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  Investigating the association between diabetes mellitus, depression and psychological distress in a cohort of South African teachers 

  Domingo, Abdul Kader; Asmal, Laila; Seedat, Soraya; Esterhuizen, Tonya M.; Laurence, Carien; Volmink, Jimmy (Health & Medical Publishing Group, 2015-11)

  Background. Diabetes mellitus (DM) may increase the risk of depression as a result of a sense of threat of debilitating complications or because of associated lifestyle changes. Depression may increase the risk of type 2 ...
  
  
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  World Health Organization guidelines for management of acute stress, PTSD, and bereavement : key challenges on the road ahead 

  Tol, Wietse A.; Barbui, Corrado; Bisson, Jonathan; Cohen, Judith; Hijazi, Zeinab; Jones, Lynne; De Jong, Joop T. V. M.; Magrini, Nicola; Omigbodun, Olayinka; Seedat, Soraya; Silove, Derrick; Souza, Renato; Sumathipala, Athula; Vijayakumar, Lakshmi; Weissbecker, Inka; Zatzick, Douglas; Van Ommeren, Mark (PLoS, 2014-12)

  The implementation of new WHO mental health guidelines for conditions and disorders specifically related to stress is likely to face obstacles, particularly in low- and middle-income countries. N Formulation of ...
  
  
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  The impact of alcohol on HIV prevention and treatment for South Africans in primary healthcare 

  Schneider, Michelle; Chersich, Matthew; Temmerman, Marleen; Degomme, Olivier; Parry, Charles D. (AOSIS Publishing, 2014-08-01)

  Background: Antiretroviral treatment (ART) has substantially reduced morbidity and mortality for HIV patients. In South Africa, with the largest ART programme globally, attention is needed not only on the further expansion ...
  
  
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  Alcohol use, working conditions, job benefits, and the legacy of the "Dop" system among farm workers in the Western Cape Province, South Africa : hope despite high levels of risky drinking 

  Gossage, J. Phillip; Snell, Cudore L.; Parry, Charles D. H.; Marais, Anna-Susan; Barnard, Ronel; De Vries, Marlene; Blankenship, Jason; Seedat, Soraya; Hasken, Julie M.; May, Philip A. (MDPI, 2014-07)

  This study describes alcohol consumption in five Western Cape Province communities. Cross-sectional data from a community household sample (n = 591) describe the alcohol use patterns of adult males and females, and farm ...
  
  
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  Legalising medical use of cannabis in South Africa : is the empirical evidence sufficient to support policy shifts in this direction? 

  Parry, C. D. H.; Myers, B. J. (Health & Medical Publishing Group, 2014-06)

  Inkatha Freedom Party MP Mario Oriani-Ambrosini’s impassioned plea to legalise the medical use of cannabis must be understood in the context of his own condition as well as legislative changes in at least ten countries. ...
  
  
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  Mandatory reporting of child abuse in South Africa : legislation explored 

  Hendricks, Melany Leonie (Health & Medical Publishing Group, 2014-08)

  Legislation concerning mandatory reporting of child abuse in South Africa has been in effect since 2010, with the promulgation of amendment 41 of 2007 to the Children’s Act of 2005. This article explores mandatory reporting ...
  
  
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  A prospective study of clinical, biological and functional aspects of outcome in first episode psychosis 

  Chiliza, Bonginkosi (Stellenbosch : Stellenbosch University, 2015-12)

  ENGLISH ABSTRACT: Prospective, longitudinal clinical studies in first-episode schizophrenia have become relatively commonplace over the past two decades or more and have provided a wealth of useful information regarding ...
  
  
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  Assessing post-traumatic stress disorder in South African adolescents : using the child and adolescent trauma survey (CATS) as a screening tool 

  Suliman, S.; Kaminer, D.; Seedat, S.; Stein, D. J. (BioMed Central, 2005-01)

  Background: Several studies have demonstrated that South African children and adolescents are exposed to high levels of violent trauma with a significant proportion developing PTSD, however, limited resources make it ...
  
  
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  An analysis of early developmental trauma in social anxiety disorder and posttraumatic stress disorder 

  Bishop, Melanie; Rosenstein, David; Bakelaar, Susanne; Seedat, Soraya (BioMed Central, 2014-05)

  Background: The early contributions of childhood trauma (emotional, physical, sexual, and general) have been hypothesized to play a significant role in the development of anxiety disorders, such as posttraumatic ...
  
  
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  Facial affect recognition and exit examination performance in medical students : a prospective exploratory study 

  Roos, Tessa C.; Niehaus, Dana J. H.; Leppanen, Jukka M.; Ras, Johan; Cloete, Karen J.; Jordaan, Esme; Koen, Liezl (BioMed Central, 2014-11)

  Background: Facial affect recognition (FAR) abilities underpin emotional intelligence (EI). The latter is suggested to predict academic success and to be important for clinician-patient interaction. It is therefore ...
  
  
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  Clinical and neuropsychological predictors of posttraumatic stress disorder 

  Suliman, Sharain; Stein, Dan J.; Seedat, Soraya (Lippincott, Williams & Wilkins, 2014-11)

  Abstract: Although acute responses to traumatic stress generally resolve within a few weeks, some individuals experience severe and persistent problems, such as posttraumatic stress disorder (PTSD). While studies have ...
  
  
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  Neurocognition and thought disorder : it’s association, temporal stability and outcome correlates in first-episode psychosis 

  Olivier, Marius Riaan (Stellenbosch : Stellenbosch University, 2015-04)

  ENGLISH ABSTRACT: Abstract Neurocognitive deficits and thought disorder in schizophrenia have generally been accepted as core features of the illness, yet their underlying relationship, response to treatment, and ...
  
  
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  The identification of novel susceptibility genes involved in anxiety disorders 

  McGregor, Nathaniel Wade (Stellenbosch : Stellenbosch UniversityStellenbosch University, 2014-12)

  ENGLISH ABSTRACT: The etiology of anxiety disorders remains incompletely understood. Clear evidence for a genetic component has been proposed; however, there is also an increasing focus on environmental factors and the ...
  
  
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  Frequency and correlates of co-morbid psychiatric illness in patients with heroin use disorder admitted to Stikland Opioid Detoxification Unit, South Africa 

  Dannatt, Lisa Gwen; Weich, Lize (Health and Medical Publishing Group, 2014-08)

  Background. There is a lack of studies addressing the frequency and correlates of co-morbidities among heroin users admitted for treatment in South Africa. Objective. To assess the frequency and correlates of psychiatric ...
  
  
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  Incidence of anxiety and depression in a predominantly HIV-infected population with severe adverse drug reactions 

  Zitha, Eddy; Chiliza, Bonga; Muloiwa, Rudzani; Lehloenya, Rannakoe (BioMed Central, 2014-07)

  Background Little is known on the short-term or medium-term psychological and psychiatric sequelae following Stevens Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug reaction with eosinophilia and ...
  
  
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  Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture 

  Davis, Lea K.; Yu, Dongmei; Keenan, Clare L.; Gamazon, Eric R.; Konkashbaev, Anuar I.; Derks, Eske M.; Neale, Benjamin M.; Yang, Jian; Lee, S. Hong; Evans, Patrick; Barr, Cathy L.; Bellodi, Laura; Benarroch, Fortu; Berrio, Gabriel Bedoya; Bienvenu, Oscar J.; Bloch, Michael H.; Blom, Rianne M.; Bruun, Ruth D.; Budman, Cathy L.; Camarena, Beatriz; Campbell, Desmond; Cappi, Carolina; Silgado, Julio C. Cardona; Cath, Danielle C.; Cavallini, Maria C.; Chavira, Denise A.; Chouinard, Sylvain; Conti, David. V.; Cook, Edwin H.; Coric, Vladimir; Cullen, Bernadette A.; Deforce, Dieter; Delorme, Richard; Dion, Yves; Edlund, Christopher K.; Egberts, Karin; Falkai, Peter; Fernandez, Thomas V.; Gallagher, Patience J.; Garrido, Helena; Geller, Daniel; Girard, Simon L.; Grabe, Hans J.; Grados, Marco A.; Greenberg, Benjamin D.; Gross-Tsur, Varda; Haddad, Stephen; Heiman, Gary A.; Hemmings, Sian M. J.; Hounie, Ana G.; Illmann, Cornelia; Jankovic, Joseph; Jenike, Michael A.; Kennedy, James L.; King, Robert A.; Kremeyer, Barbara; Kurlan, Roger; Lanzagorta, Nuria; Leboyer, Marion; Leckman, James F.; Lennertz, Leonhard; Liu, Chunyu; Lochner, Christine; Lowe, Thomas L.; Macciardi, Fabio; McCracken, James T.; McGrath, Lauren M.; Mesa Restrepo, Sandra C.; Moessner, Rainald; Morgan, Jubel; Muller, Heike; Murphy, Dennis L.; Naarden, Allan L.; Ochoa, William Cornejo; Ophoff, Roel A.; Osiecki, Lisa; Pakstis, Andrew J.; Pato, Michele T.; Pato, Carlos N.; Piacentini, John; Pittenger, Christopher; Pollak, Yehuda; Rauch, Scott L.; Renner, Tobias J.; Reus, Victor I.; Richter, Margaret A.; Riddle, Mark A.; Robertson, Mary M.; Romero, Roxana; Rosario, Maria C.; Rosenberg, David; Rouleau, Guy A.; Ruhrmann, Stephan; Ruiz-Linares, Andres; Sampaio, Aline S.; Samuels, Jack; Sandor, Paul; Sheppard, Brooke; Singer, Harvey S.; Smit, Jan H.; Stein, Dan J.; Strengman, E.; Tischfield, Jay A.; Valencia Duarte, Ana V.; Vallada, Homero; Van Nieuwerburgh, Filip; Veenstra-VanderWeele, Jeremy; Walitza, Susanne; Wang, Ying; Wendland, Jens R.; Westenberg, Herman G. M.; Shugart, Yin Yao; Miguel, Euripedes C.; McMahon, William; Wagner, Michael; Nicolini, Humberto; Posthuma, Danielle; Hanna, Gregory L.; Heutnik, Peter; Denys, Damiaan; Arnold, Paul D.; Oostra, Ben A.; Nestadt, Gerald; Freimer, Nelson B.; Pauls, David L.; Wray, Naomi R.; Stewart, S. Evelyn; Mathews, Carol A.; Knowles, James A.; Cox, Nancy J.; Shcarf, Jeremiah M. (PLoS, 2013-10)

  The direct estimation of heritability from genome-wide common variant data as implemented in the program Genome-wide Complex Trait Analysis (GCTA) has provided a means to quantify heritability attributable to all interrogated ...
  
  
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  Trauma exposure, posttraumatic stress disorder and the effect of explanatory variables in paramedic trainees 

  Fjeldheim, Celine B.; Nothling, Jani; Pretorius, Karin; Basson, Marina; Ganasen, Keith; Heneke, Robin; Cloete, Karen J.; Seedat, Soraya (BioMed Central, 2014-04)

  Abstract Background: Emergency healthcare workers, including trainees and individuals in related occupations are at heightened risk of developing posttraumatic stress disorder (PTSD) and depression owing to work-related ...
  
  
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  Molecular mechanisms of D-cycloserine in a fear extinction posttraumatic stress disorder (PTSD) animal model 

  Malan-Muller, Stefanie (Stellenbosch : Stellenbosch University, 2014-04)

  ENGLISH ABSTRACT: Posttraumatic stress disorder (PTSD) is a severe, chronic and debilitating psychiatric disorder that can present after the experience of a life-threatening traumatic event. D-cycloserine (DCS), a partial ...
  
  
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  A prospective study of neurological abnormalities in a cohort of Nigerian patients with schizophrenia 

  Ojagbemi, Abel Akinsola (Stellenbosch : Stellenbosch University, 2014-04)

  ENGLISH ABSTRACT: Background The changes in cognition, brain structure, and neurological soft signs which are characteristic of schizophrenia appear to have been present before the onset of the phenotype. They therefore ...
  
  
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  Subtyping schizophrenia 

  Niehaus, Daniel Jan Hendrik (Stellenbosch : Stellenbosch University, 2014-04)

  ENGLISH ABSTRACT: Schizophrenia is a phenotypically heterogeneous disorder believed to have a strong genetic component. Limiting its clinical heterogeneity by means of subtyping may help to shed light on some of the genetic ...
  
  

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