Department of Psychiatry
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The burden of mental disorders in the Eastern Mediterranean Region, 1990-2013
(Public Library of Science, 2017)The Eastern Mediterranean Region (EMR) is witnessing an increase in chronic disorders, including mental illness. With ongoing unrest, this is expected to rise. This is the first study to quantify the burden of mental ... -
Once-monthly paliperidone palmitate in early stage schizophrenia – a retrospective, non-interventional 1-year study of patients with newly diagnosed schizophrenia
(Dove Medical Press, 2017)Background: Long-acting antipsychotic therapy may be best suited for patients in the early stage of schizophrenia, when the most can be done before disease progression associated with poor adherence occurs. We explored the ... -
Excoriation (skin-picking) disorder : a systematic review of treatment options
(Dove Medical Press, 2017)Although pathological skin-picking has been documented in the medical literature since the 19th century, it has only recently been included as a distinct entity in psychiatric classification systems. In the Diagnostic and ... -
Prolonged exposure therapy and supportive counselling for posttraumatic stress disorder in adolescents in a community-based sample, including experiences of stakeholders : study protocol for a comparative randomized controlled trial using task-shifting
(BMC (part of Springer Nature), 2018-09-06)Background: There is a dearth of empirical evidence on the effectiveness of pharmacological and non-pharmacological treatments for adolescents with posttraumatic stress disorder (PTSD) in developing countries. The primary ... -
Study protocol for a longitudinal study evaluating the impact of rape on women's health and their use of health services in South Africa
(BMJ Publishing Group, 2017-09)Introduction South Africa is a country known for its high levels of HIV infection and sexual violence. Although the interface between gender-based violence, HIV and mental health has been described, there are substantial gaps ... -
Integrated community case management of childhood illness in low- and middle-income countries
(John Wiley & Sons, Ltd. on behalf of The Cochrane Collaboration, 2017)This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the effects of the integrated community case management (iCCM) strategy for children younger than five years of age in ... -
The socioeconomic profile of alcohol-attributable mortality in South Africa : a modelling study
(BioMed Central, 2018-06-25)Background: Globally, illness and life expectancy follow a social gradient that puts people of lower socioeconomic status (SES) at higher risk of dying prematurely. Alcohol consumption has been shown to be a factor ... -
Validation of the posttraumatic stress disorder checklist – 5 (PCL-5) in a primary care population with high HIV prevalence in Zimbabwe
(BioMed Central, 2018-04-23)Background: There is a dearth of validated tools measuring posttraumatic stress disorder (PTSD) in low and middleincome countries in sub-Saharan Africa. We validated the Shona version of the PTSD Checklist for DSM-5 (PCL-5) ... -
A comparative analysis of pharmacists’ perspectives on codeine use and misuse – a three country survey
(BioMed Central, 2018-03-27)Background: The misuse of codeine is of increasing concern in a number of countries, particularly as this relates to over -the-counter pain and cough relief medication, and is also supplied as a prescription medicine. The ... -
The relationship between childhood adversity, recent stressors, and depression in college students attending a South African university
(BioMed Central, 2018-03-09)Background: College students are at risk of depression. This risk may be increased by the experience of childhood adversity and/or recent stressors. This study examined the association between reported experiences of ... -
Impact of district mental health care plans on symptom severity and functioning of patients with priority mental health conditions : the Programme for Improving Mental Health Care (PRIME) cohort protocol
(BioMed Central, 2018-03-06)Background: The Programme for Improving Mental Health Care (PRIME) sought to implement mental health care plans (MHCP) for four priority mental disorders (depression, alcohol use disorder, psychosis and epilepsy) into ... -
Brain structural and white matter changes in first-episode schizophrenia and their demographic, clinical and cognitive correlates
(Stellenbosch : Stellenbosch University, 2018-03)ENGLISH SUMMARY : In schizophrenia, decreased brain volume and altered cortical thinning (especially in the frontal and temporal areas), as well as white matter deficits are described at the first-episode. The relationship ... -
Participants’ perspectives of weekly telephonic mood monitoring in South Africa : a feasibility study
(BioMed Central, 2018-02-22)Background: Mood and anxiety disorders have a high lifetime prevalence, and their chronicity adds to the management burden of already scarce and strained mental health care resources, particularly in developing countries. ... -
Replication of high fetal alcohol spectrum disorders prevalence rates, child characteristics, and maternal risk factors in a second sample of rural communities in South Africa
(MDPI, 2017)Background: Prevalence and characteristics of fetal alcohol syndrome (FAS) and total fetal alcohol spectrum disorders (FASD) were studied in a second sample of three South African rural communities to assess change. Methods: ... -
An examination of differences in psychological resilience between social anxiety disorder and posttraumaic stress disorder in the context of early childhood trauma
(Frontiers, 2017-12)ENGLISH SUMMARY : Background: Much of the research on anxiety disorders has focused on associated risk factors with less attention paid to factors such as resilience that may mitigate risk or offer protection in the face ... -
Association between motor timing and treatment outcomes in patients with alcohol and/or cocaine addiction in a rehabilitation programme
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Introduction: Motor timing deficits have been found in DA system related disorders and, more recently, also in individuals with Substance Use Disorders (SUD). Motor timing is fundamental to our ability ... -
Correction to : The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts : a cross sectional study
(BioMed Central, 2017-11-07)Correction: After publication of the original article [1] the authors noted that the following errors had occurred: The name of the author H. Simon Schaaf had been incorrectly tagged as Simon H. Schaaf. This has ... -
Relationship between childhood trauma, neuropsychological deficits, neural circuitry, and anxiety proneness in high-anxiety prone and low-anxiety prone adolescents
(Stellenbosch : Stellenbosch University, 2017-12)ENGLISH SUMMARY : Anxiety disorders, which commonly have their onset during critical developmental periods of childhood, adolescence and early adulthood, are associated with high rates of comorbidity, chronicity, and ... -
Prevalence and correlates of non-medical stimulants and related drug use in a sample of South African undergraduate medical students
(AOSIS Publishing, 2016)Background: The non-medical use of prescription psychostimulants or cognitive-enhancing substances among healthy college students is a growing concern. This use appears to be particularly high among medical students. To ... -
Developing the language of futility in psychiatry with care
(AOSIS Publishing, 2016)In psychiatric practice, treatment success is, in many instances, not an achievable goal. Psychiatrists may often not acknowledge treatment failure in their patients and seldom consider that patients may be in situations ...
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