Department of Paediatrics and Child Health
Collections in this community
Recent Submissions
-
Isoniazid Preventive Therapy in HIV-Infected Pregnant and Postpartum Women
(Massachusetts Medical Society, 2019-10-03)BACKGROUND: The safety, efficacy, and appropriate timing of isoniazid therapy to prevent tuberculosis in pregnant women with human immunodeficiency virus (HIV) infection who are receiving antiretroviral therapy are ... -
Identification of an iron-responsive subtype in two children diagnosed with relapsing-remitting multiple sclerosis using whole exome sequencing
(Elsevier, 2019-06)Background: Multiple sclerosis is a disorder related to demyelination of axons. Iron is an essential cofactor in myelin synthesis. Previously, we described two children (males of mixed ancestry) with relapsing-remitting ... -
Tuberculous meningitis in children is characterized by compartmentalized immune responses and neural excitotoxicity
(Nature Research (part of Springer Nature), 2019)ENGLISH ABSTRACT: Tuberculous meningitis (TBM) is the most severe form of TB with high rates of mortality and morbidity. Here we conduct RNA-sequencing on whole blood as well as on ventricular and lumbar cerebrospinal fluid ... -
A child with perinatal HIV infection and long-term sustained virological control following antiretroviral treatment cessation
(Nature Research (part of Springer Nature), 2019)ENGLISH ABSTRACT: Understanding HIV remission in rare individuals who initiated antiretroviral therapy (ART) soon after infection and then discontinued, may inform HIV cure interventions. Here we describe features of virus ... -
Asthma treatment in children : a guide to screening for and management of hypothalamic-pituitary-adrenal axis suppression
(Health & Medical Publishing Group, 2019)ENGLISH ABSTRACT: A recently published approach to paediatric asthma management neither recommended screening for nor suggested any management of hypothalamic-pituitary-adrenal axis suppression in asthmatic children treated ... -
The impact of health programmes to prevent vertical transmission of HIV. Advances, emerging health challenges and research priorities for children exposed to or living with HIV : perspectives from South Africa
(Health & Medical Publishing Group, 2019)ENGLISH ABSTRACT: Over the past three decades, tremendous global progress in preventing and treating paediatric HIV infection has been achieved. This paper highlights the emerging health challenges of HIV-exposed uninfected ... -
Acquired neonatal bronchial stenosis after selective intubation : successful managed with balloon dilatation
(Wiley Open Access, 2019)ENGLISH ABSTRACT: Premature babies are prone to airway‐related complications. Selective intubation for the management of pulmonary interstitial emphysema may cause acquired bronchial stenosis. Balloon dilatation under ... -
Corrosive injury of the trachea in children
(Wiley Open Access, 2019)ENGLISH ABSTRACT: The secondary injury may present weeks to months after the initial insult and repeat bronchoscopy, and long‐term follow‐up is required for the respiratory complications of CSI. Ingestion of caustic fluid ... -
The impact of a diabetes care team on the glycaemic control of paediatric and adolescent patients with type 1 diabetes mellitus at Tygerberg Children’s Hospital
(Health & Medical Publishing Group, 2019-04-11)Background. A diabetes care team (DCT) may contribute to improved glycaemic control in type 1 diabetes mellitus (T1DM) patients. Hence a DCT was introduced at Tygerberg Children’s Hospital (TCH) in 2009. Hypothesis. A ... -
Neonatal hypotension survey : a South African perspective
(Health & Medical Publishing Group, 2019-06-25)Background. Neonatal hypotension remains one of the most controversial topics in neonatology. Various definitions are used but lack an evidence base. Owing to the variation in defining a low blood pressure (BP), significant ... -
A prospective study of the immune reconstitution inflammatory syndrome (IRIS) in HIV-infected children from high prevalence countries
(PLoS, 2019-07-01)Background: The immune reconstitution inflammatory syndrome (IRIS) in HIV-infected infants and young children is relatively understudied in regions endemic for HIV and TB. We aimed to describe incidence, clinical features ... -
Burkitt lymphoma : trends in children below 15 years reveal priority areas for early diagnosis activities in north-west Cameroon
(AOSIS, 2019)Background: Burkitt lymphoma is one of the most common childhood cancers in Cameroon. Incidence rates of 5.9/100 000 and 2.58 per 100 000 have been reported in two studies in 2005 and 2012 amongst children below 15 years ... -
Working together to build a better future for children with cancer in Africa
(American Society of Clinical Oncology, 2020)ENGLISH ABSTRACT: No abstract available -
Data collection in the Collaborative Wilms Tumour Africa Project
(Elsevier, 2018)ENGLISH ABSTRACT: No abstract available -
The outcome and cost of a capacity-building training programme on the early recognition and referral of childhood cancer for healthcare workers in North-West Cameroon
(John Wiley & Sons Ltd, 2020)Aim: Early cancer diagnosis is necessary to improve survival rates. The aim of this study was to assess the outcome and cost of the childhood cancer training programme amongst healthcare workers. Design: This was a ... -
An ethical imperative : safety and specialization as nursing priorities of WHO Global Initiative for Childhood Cancer
(Wiley Periodicals, Inc., 2019)ENGLISH ABSTRACT: Abstract not available -
Highlights from the 13th African continental meeting of the International Society of Paediatric Oncology (SIOP), 6–9 March 2019, Cairo, Egypt
(ecancermedicalscience, 2019)ENGLISH ABSTRACT: The 13th African continental meeting of the international society of paediatric oncology, held on 6–9 March 2019 in Cairo, was organised in collaboration with the Children Cancer Hospital (57357) in ... -
Management of neuroblastoma in limited-resource settings
(Baishideng Publishing Group Inc., 2020)BACKGROUND: Neuroblastoma (NB) is a heterogeneous disease with variable outcomes among countries. Little is known about NB in low- and middle-income countries (LMICs). AIM: The aim of this review was to evaluate ... -
Validity and feasibility of the self-report EQ-5D-Y as a generic Health-Related Quality of Life outcome measure in children and adolescents with Juvenile Idiopathic Arthritis in Western Cape, South Africa
(AOSIS, 2019)Background: Health-Related Quality of Life (HRQoL) data together with clinical findings allow for monitoring of intervention efficacy and the effect on HRQoL. Children with Juvenile Idiopathic Arthritis (JIA) experience ... -
Improving early diagnosis and referrals to life-saving care for children with cancer in Cameroon
(Stellenbosch : Stellenbosch University, 2021-03)ENGLISH ABSTRACT: Childhood cancer is curable, but survival rates in low- and middle-income countries (LMICs), especially sub-Saharan Africa, are generally low. In 2018, the International Society of Paediatric ...
RSS 1.0