Department of Obstetrics and Gynaecology
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A case series of post-partum haemorrhage managed using Ellavi uterine balloon tamponade in a rural regional hospital
(AOSIS, 2021-05)Uterine balloon tamponade (UBT) should be attempted once emergency measures have been applied and medical treatment for post-partum haemorrhage (PPH) resulting from an atonic uterus has failed. Sinapi Biomedical (Pty) Ltd ... -
Incidence, management, and outcomes of pregnancies complicated by major placenta praevia at Tygerberg Hospital: A two-year review
(Stellenbosch : Stellenbosch University, 2022-11-21)ENGLISH ABSTRACT: Introduction Obstetric haemorrhage is the third most important cause of direct maternal death (19,1% of all deaths) in South Africa. Although most of these deaths are due to postpartum haemorrhage, ... -
A critical analysis of preterm birth in a largely homogeneous community near Tygerberg Academic Hospital with a high prevalence of preterm birth
(Stellenbosch : Stellenbosch University, 2022-11)ENGLISH ABSTRACT: There is a high priority to address the heavy burden of preterm birth (PTB) on a low- to middle- class community in the Western Cape Province of South Africa (SA), where the Safe Passage Study (SPS) by ... -
Outcomes of monoamniotic twin pregnancies at Tygerberg Hospital : a ten-year review
(Stellenbosch : Stellenbosch University, 2022-11)ENGLISH ABSTRACT: Background: Monoamniotic twin pregnancies (MATPs) are at high risk of antenatal and perinatal complications including fetal loss. There is still no consensus regarding the optimal management strategies, ... -
Prevalence of high-grade squamous intraepithelial lesion within two years of large loop excision of the transformation zone at a tertiary hospital colposcopy clinic in Cape Town
(Stellenbosch : Stellenbosch University, 2022-11)ENGLISH ABSTRACT: Background Large loop excision of the transformation zone (LLETZ) has become widely accepted as the technique of choice for the treatment of cervical intraepithelial neoplasia. Despite its high efficacy ... -
A profile of surgical complications in gynaecology at a teaching hospital in South Africa
(Stellenbosch : Stellenbosch University, 2022-11)ENGLISH ABSTRACT: Background and Aim Information about current gynaecological surgical practices and patient outcomes is integral to the provision of quality gynaecological care. An audit of surgical complications can ... -
Using a composite maternal-infant outcome measure in tuberculosis prevention studies among pregnant women
(Oxford University Press, 2021-08-02)Background: Tuberculosis (TB-)-preventive therapy (TPT) among pregnant women reduces risk of TB in mothers and infants, but timing of initiation should consider potential adverse effects. We propose an analytical approach ... -
Pregnancy outcomes of women conceiving on antiretroviral therapy (ART) compared to those commenced on ART during pregnancy
(Oxford University Press, 2021-07)Background: Globally, the number of infected women of childbearing age living with human immunodeficiency virus (HIV) and conceiving on antiretroviral therapy (ART) is increasing. Evidence of ART safety at conception and ... -
Individual and composite adverse pregnancy outcomes in a randomized trial on isoniazid preventative therapy among women living with human immunodeficiency virus
(Oxford University Press, 2021-06-01)Background: International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) P1078, a randomized noninferiority study designed to compare the safety of starting isoniazid preventive therapy (IPT) in women living ... -
Effects of pregnancy and isoniazid preventive therapy on mycobacterium tuberculosis interferon gamma response assays in women with HIV
(Oxford University Press, 2020-07)Background Pregnancy is accompanied by immune suppression. We hypothesized that Mycobacterium tuberculosis-specific inflammatory responses used to identify latent tuberculosis infection (LTBI) lose positivity during ... -
Transitional objects of grief
(Comprensive Psychiatry, 2020-01)Background: Transitional objects provide security and symbolic connection with valued others when separated from them. Bereaved parents often keep, cherish and visit saved objects of their deceased child. This research ... -
Human oocyte and ovarian tissue vitrification in fertility preservation for women: an audit and prospective study
(Stellenbosch : Stellenbosch University, 2022-04)ENGLISH SUMMARY: Introduction: Female fertility preservation [FP] is of interest, due to the advancement in cancer therapy and the resultant increased survival rate. Methods of FP include embryo vitrification, oocyte ... -
Additional value of advanced neurosonography and magnetic resonance imaging in fetuses at risk for brain damage
(John Wiley & Sons, 2020)Objective: To assess the additional value of fetal multiplanar (axial, coronal and sagittal) neurosonography and magnetic resonance imaging (MRI) to that of the standard axial ultrasound planes in diagnosing brain damage ... -
INTERGROWTH-21st v. local South African growth standards (Theron-Thompson) for identification of small-for-gestational-age fetuses in stillbirths : a closer look at variation across pregnancy
(Health & Medical Publishing Group, 2019)Background. Global growth standards for fetuses were recently developed (INTERGROWTH-21st). It has been advocated that professional bodies should adopt these global standards. Objectives. To compare the ability of ... -
Evidence of neuroinflammation and blood–brain barrier disruption in women with preeclampsia and eclampsia
(MDPI, 2021-11-05)ENGLISH ABSTRACT: Cerebral complications in preeclampsia are leading causes of maternal mortality. Animal models suggest that an injured blood–brain barrier and neuroinflammation may be important but there is paucity of ... -
Neural tube defect diagnosis and outcomes at a tertiary South African hospital with intensive case ascertainment
(Health & Medical Publishing Group, 2019)Background. Neural tube defects (NTDs) are an important category of birth defect, but surveillance remains inadequate in South Africa. Objectives. To assess the identification of NTDs at a tertiary hospital using a range ... -
Endometrial cancer in young women. A retrospective matched cohort study.
(Stellenbosch : Stellenbosch University, 2021-12)ENGLISH ABSTRACT: OBJECTIVE: Endometrial cancer is the second most common gynaecological cancer in South Africa. It typically arises in the sixth and seventh decades of life. However, an increasing number of premenopausal ... -
Early onset pre-eclampsia with severe features necessitating fetal delivery: outcome of pregnancies with birthweight 1000-1800g at Tygerberg Hospital 2017
(Stellenbosch : Stellenbosch University, 2021-12)Introduction: Expectant management of early onset pre-eclampsia (EOPE) is an established practice at Tygerberg Hospital and some other tertiary institutions in South Africa. Its outcome has been documented in several ... -
Outcomes of assisted reproductive technologies in women 40 years and older at Tygerberg Hospital
(Stellenbosch : Stellenbosch University, 2021-12)Objective: To evaluate the outcomes of ART in women age of 40 years and above Design: Retrospective descriptive study Setting: Tygerberg Academic Hospital, Reproductive Medicine Unit Population: All women aged 40 years ... -
Pain management protocol for oocyte retrieval in low-resource setting assisted reproductive technology: Patient survey
(Stellenbosch : Stellenbosch University, 2021-12)Introduction: Assisted reproductive technology (ART) involves a series of procedures, the cost of which may prevent many from achieving reproduction desire s. To cut on the cost , oocyte retrieval has evolved into an ...
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