Department of Medicine
Sub-communities within this community
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Cardiology [67]
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Dermatology [8]
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Endocrinology [9]
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Gastroenterology [5]
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General Medicine [41]
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Infectious Diseases [28]
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Nephrology [33]
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Neurology [14]
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Pulmonology [41]
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Rheumatology [6]
Recent Submissions
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Post-tuberculosis health-related quality of life, lung function and exercise capacity in a cured pulmonary tuberculosis population in the Breede Valley District, South Africa
(AOSIS, 2019)Background: Pulmonary tuberculosis (PTB) remains a major concern worldwide. Albeit curable, PTB continues to negatively affect patients’ health-related quality of life (HRQoL) and functioning even after cure. Objectives: To ... -
Incident tuberculosis disease in patients receiving biologic therapies in the Western Cape, South Africa from 2007 to 2018
(BMC (part of Springer Nature), 2019)Background: South Africa has one of the highest tuberculosis incidence rates. Biologic disease-modifying antirheumatic drugs are associated with an increased risk of tuberculosis. The objective of this study was to ... -
Interventional cardiology during the COVID-19 epidemic
(South African Heart Association, 2020)ENGLISH ABSTRACT: The impact of the COVID-19 pandemic on our lives is unprecedented and major adjustments to our practices as physicians are required. Although our comments are applicable at the time of writing, the situation ... -
Arrhythmias and COVID-19 infection
(South African Heart Association, 2020)ENGLISH ABSTRACT: Arrhythmias can be a clinical manifestation of COVID-19 infection. COVID-19 infection can also be a precipitant of known arrhythmias which can increase the risk of morbidity and mortality. Management of ... -
Developing a new electrophysiology service and training platform - narrowing the gap
(South African Heart Association, 2020)No abstract available. -
COVID-19 and cardiovascular imaging : a guide for the practising clinician
(South African Heart Association, 2020)ENGLISH ABSTRACT: In the ongoing COVID-19 pandemic, patients with cardiac disease have been the worst affl icted with a high mortality. Cardiac imaging forms an integral part of the armamentarium in the management of ... -
Guidelines for the prevention, detection and management of the renal complications of COVID-19 in Africa
(African Association of Nephrology, 2020)ENGLISH ABSTRACT: Africa trails the rest of the world in COVID-19 cases and deaths. However, as the pandemic spreads through the continent, we expect increases in community infection in the months ahead. Patients with ... -
The rise and fall of hydroxychloroquine for the treatment and prevention of COVID-19
(American Society of Tropical Medicine and Hygiene, 2021)ENGLISH ABSTRACT: The efficacy and safety of hydroxychloroquine (HCQ) for the prevention and treatment of COVID-19 has received great attention, and most notably, the enthusiasm for HCQ has been one of politicization ... -
Diabetes mellitus and COVID-19 : a review and management guidance for South Africa
(Health & Medical Publishing Group, 2020-08)ENGLISH ABSTRACT: This article reviews the association between diabetes mellitus (DM) and COVID-19. We report on the convergence of infectious diseases such as coronavirus infections and non-communicable diseases including ... -
Meta-analysis on outcome-worsening comorbidities of COVID-19 and related potential drug-drug interactions
(Elsevier, 2020-11)ENGLISH ABSTRACT: Drug-drug interactions (DDI) potentially occurring between medications used in the course of COVID-19 infection and medications prescribed for the management of underlying comorbidities may cause adverse ... -
The colliding epidemics of COVID-19, Ebola, and measles in the Democratic Republic of the Congo
(Elsevier, 2020)ENGLISH ABSTRACT: The Democratic Republic of the Congo is facing major public health challenges due to a confluence of major outbreaks of Ebola virus disease, measles, and COVID-19.1–4 The tenth Ebola outbreak in eastern ... -
Clinical trials of disease stages in COVID 19 : complicated and often misinterpreted
(Elsevier, 2020-08-20)As of July 28, 2020, 1840 clinical trials were registered globally, with 1001 clinical trials recruiting patients for COVID-19 management.1 Despite this large number, only 30 trials have been published as peer-reviewed or ... -
Clinical characteristics and outcomes of patients hospitalized for COVID-19 in Africa : early insights from the Democratic Republic of the Congo
(American Society of Tropical Medicine and Hygiene, 2020)ENGLISH ABSTRACT: Little is known about the clinical features and outcomes of SARS-CoV-2 infection in Africa. We conducted a retrospective cohort study of patients hospitalized for COVID-19 between March 10, 2020 and July ... -
Exploring the factors that affect new graduates’ transition from students to health professionals : a systematic integrative review protocol
(BMJ Publishing Group, 2020-05-15)Introduction: To become a competent health professional, the nature of new graduates’ transition plays a fundamental role. The systematic integrative review will aim to identify the existing literature pertaining to the ... -
Echocardiographic screening for subclinical rheumatic heart disease: Improving screening through simplification of the diagnostic criteria
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH ABSTRACT: Rheumatic heart disease (RHD) remains one of the leading causes of cardiovascular morbidity and mortality in developing countries withSub-Saharan Africa being identified as an endemic area. The early ... -
Lupus myocarditis : diagnostic characteristics and outcome of myocardial injury
(Stellenbosch : Stellenbosch University, 2020-12)ENGLISH ABSTRACT: Lupus myocarditis is a rare but serious manifestation of systemic lupus erythematosus (SLE). Through this dissertation I have aimed to describe the outcome of both clinical as well as subclinical ... -
In vitro assessment of the interaction potential of ocimum basilicum (L.) extracts on CYP2B6, 3A4, and rifampicin metabolism
(Frontiers Media, 2020-04-30)ENGLISH ABSTRACT: Ocimum basilicum L. or basilicum is a common culinary herb, used as a traditional medicine for various medical conditions including HIV/AIDS and tuberculosis, in Africa. The objective of this study was ... -
Flower cells in patient with HTLV1 associated adult T-cell leukaemia/lymphoma
(Oxford University Press, 2020-10-04)ENGLISH ABSTRACT: No abstract available. -
A population pharmacokinetic model is beneficial in quantifying hair concentrations of ritonavir-boosted atazanavir : a study of HIV-infected Zimbabwean adolescents
(BMC, 2020-08-03)Background: Adolescents experience higher levels of non-adherence to HIV treatment. Drug concentration in hair promises to be reliable for assessing exposure to antiretroviral (ARV) drugs. Pharmacokinetic modelling can ... -
Staff testing for COVID-19 via an online pre-registration form
(medRxiv, 2020)Background: Healthcare workers are at increased risk of contracting SARS-CoV-2 and potentially causing institutional outbreaks. Staff testing is critical in identifying and isolating infected individuals while also reducing ...
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