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Virological response without CD4 recovery. A case of disappearing soldiers - Can basic science help?

dc.contributor.authorMadide A.
dc.contributor.authorRabie H.
dc.contributor.authorCotton M.
dc.date.accessioned2011-05-15T16:18:10Z
dc.date.available2011-05-15T16:18:10Z
dc.date.issued2006
dc.identifier.citationSouthern African Journal of HIV Medicine
dc.identifier.citation24
dc.identifier.issn16089693
dc.identifier.urihttp://hdl.handle.net/10019.1/14542
dc.description.abstractThe objective of antiretroviral therapy (ART) is to suppress viral replication so that immune restoration can occur. Failure of immune restoration is usually associated with poor virological suppression. In children a good immunological and clinical response to ART is often achieved despite incomplete viral suppression. However, we have recently managed a number of children in whom immune restoration did not occur despite excellent virological suppression. We present a case, discuss possible causes and speculate on the appropriate course of action.
dc.subjectantibiotic agent
dc.subjectantiretrovirus agent
dc.subjectCD4 antigen
dc.subjectcotrimoxazole
dc.subjectefavirenz
dc.subjectlamivudine
dc.subjectoxygen
dc.subjectrifampicin
dc.subjectstavudine
dc.subjecttuberculostatic agent
dc.subjectvirus RNA
dc.subjectanamnesis
dc.subjectarticle
dc.subjectatypical mycobacteriosis
dc.subjectbody weight
dc.subjectbronchiectasis
dc.subjectcase report
dc.subjectchest infection
dc.subjectclinical feature
dc.subjectdisease classification
dc.subjectdrug dose reduction
dc.subjectfollow up
dc.subjecthighly active antiretroviral therapy
dc.subjecthospital admission
dc.subjecthuman
dc.subjectHuman immunodeficiency virus infection
dc.subjectlaboratory test
dc.subjectlymphocyte count
dc.subjectmale
dc.subjectpatient compliance
dc.subjectpreschool child
dc.subjectsputum smear
dc.subjectthorax radiography
dc.subjecttreatment planning
dc.subjecttuberculin test
dc.subjecttuberculosis
dc.subjectvirus load
dc.subjectworld health organization
dc.titleVirological response without CD4 recovery. A case of disappearing soldiers - Can basic science help?
dc.typeArticle
dc.description.versionArticle


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