Cavitation of the Ghon focus in an HIV-infected infant who acquired tuberculosis after the initiation of HAART

Innes S. ; Schaaf H.S. ; Cotton M.F. (2009)


Tuberculosis immune reconstitution inflammatory syndrome (IRIS) may present as new or worsening cavitation. We present an HIV-infected infant in whom TB infection and subsequent cavitation of the Ghon focus appeared to coincide with immune reconstitution due to highly active antiretroviral therapy (HAART). TB-IRIS in response to infection that occurs after starting HAART has not previously been described.

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