Pulmonary Kaposi sarcoma in six children

Date
2007
Authors
Theron S.
Andronikou S.
Du Plessis J.
Goussard P.
George R.
Mapukata A.
Grobbelaar M.
Hayes M.
Wieselthaler N.
Davidson A.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Background: Pulmonary involvement in Kaposi sarcoma is rare in children and can be difficult to distinguish from other pathology. Objective: To describe the radiological findings in paediatric pulmonary Kaposi sarcoma. Materials and methods: Sequential chest radiographs of six children and CT scans of four of these children were evaluated retrospectively. Their ages ranged from 18 months to 10 years; four were male and two were female. All six children were HIV-positive. The observers were two radiologists. Results: Chest radiographs revealed air-space (100%) and reticular (83%) opacification in the mid- and lower lung zones; pleural effusions were present in 83% of the children. All the children showed progressive air-space opacification on follow-up radiography. CT demonstrated bilateral air-space opacification in a perihilar distribution in all the children; reticular opacification was seen in 75%. All the children had mediastinal and axillary lymphadenopathy; 75% had bilateral hilar lymphadenopathy. Conclusion: In both adults and children, chest radiography demonstrates perihilar and lower zone involvement. Pleural effusions are more common on radiographs in children. Air-space disease and lymphadenopathy are much more common on CT in children than adults. © 2007 Springer-Verlag.
Description
Keywords
article, ascites, axillary lymph node, child, clinical article, computer assisted tomography, female, follow up, human, Human immunodeficiency virus infection, image analysis, Kaposi sarcoma, lung hilus, lung metastasis, lung nodule, lymphadenopathy, male, mediastinum lymph node, pleura effusion, priority journal, radiologist, reticular formation, retrospective study, thorax radiography, Child, Child, Preschool, Humans, Infant, Lung Neoplasms, Male, Radiography, Thoracic, Sarcoma, Kaposi, Tomography, X-Ray Computed
Citation
Pediatric Radiology
37
12