Pigmenting pityriasis alba
Article
We conducted a prospective study of 20 patients with pigmenting pityriasis alba (PPA) over a period of two years. Characteristic morphology revealed a central zone of bluish hyperpigmentation surrounded by a hypopigmented, slightly scaly halo of variable width. All patients displayed lesions on the face. Concomitant extrafacial involvement was uncommon. A significant finding was an associated dermatophyte infection in 13 patients (65%). These patients all received griseofulvin 10 mg/kg/day for eight weeks, resulting in the resolution of PPA in seven within 4 to 20 weeks. These were also treated with 1% hydrocortisone. Biopsy specimens from two patients showed similar features, namely, a subacute dermatitis with variable pigment incontinence. Immunohistochemical labeling revealed a preponderance of T lymphocytes. Pigmenting pityriasis alba seems to be a variant of classic pityriasis alba showing a strong association with dermatophyte infection, especially tinea capitis. It may be related to lichenoid melanodermatitis.
Related items
Showing items related by title, author, creator and subject.
-
Consumer testing of the preliminary paediatric food-based dietary guidelines for healthy children aged 1-7 years, among English- and Afrikaans-speaking mothers in the city of Cape Town, South Africa
Scott L.D.; Marais D.; Bourne L. (2009)Objective: The aim of this qualitative study was to test the comprehensibility of the preliminary food-based dietary guidelines (FBDG) for healthy South African children aged 1-7 years. Objectives included assessing exposure ...
-
Parental response to their child's hearing impairment.
Brand H.J.; Coetzer M.A. (1994)The differential patterns of behaviour of hearing parents (30 married couples) who cope with the reality of parenting a hearing-impaired child were studied. Responses on the Questionnaire on Resources and Stress indicated ...
-
Behaviour profiles after tuberculous meningitis
Wait J.W.; Schoeman J.F. (2010)The purpose of the study was to investigate child behaviour in children who recovered from tuberculous meningitis (TBM) and to compare behaviour profiles of stage II and stage III patients. The mean age of the cohort of ...
-
Attention deficit hyperactivity and oppositional defiance disorder in HIV-infected South African children
Zeegers I.; Rabie H.; Swanevelder S.; Edson C.; Cotton M.; van Toorn R. (2010)Objective: To determine the prevalence of attention deficit-hyperactivity disorder (ADHD) and oppositional defiance disorder (ODD) in HIV-infected South African children. Methods: Swanson, Nolan and Pelham (SNAP-IV) ...
-
Psychological well-being and socio-economic hardship among AIDS orphans and other vulnerable children in Guinea
Delva W.; Vercoutere A.; Loua C.; Lamah J.; Vansteelandt S.; De Koker P.; Claeys P.; Temmerman M.; Annemans L. (2009)Over the past decade, the effects of AIDS-related parental death on children's socio-economic, educational and psychological well-being have become apparent. Most studies, however, have compared the plight of so-called ...
-
Molecular detection of mixed infections of Mycobacterium tuberculosis strains in sputum samples from patients in Karonga District, Malawi
Mallard K.; McNerney R.; Crampin A.C.; Houben R.; Ndlovu R.; Munthali L.; Warren R.M.; French N.; Glynn J.R. (2010)The occurrence of mixed infections of Mycobacterium tuberculosis is no longer disputed. However, their frequency, and the impact they may have on our understanding of tuberculosis (TB) pathogenesis and epidemiology, remains ...
-
Improvement in mycobacterial yield and reduced time to detection in pediatric samples by use of a nutrient broth growth supplement
Brittle W.; Marais B.J.; Hesseling A.C.; Schaaf H.S.; Kidd M.; Wasserman E.; Botha T. (2009)There is an urgent need to improve the methods used for the bacteriological diagnosis of childhood mycobacterial disease. This study compared the mycobacterial yields and the times to detection (in days) of mycobacteria ...
-
Interferon-gamma release assays for the detection of Mycobacterium tuberculosis infection in children with cancer
Stefan D.C.; Dippenaar A.; Detjen A.K.; Schaaf H.S.; Marais B.J.; Kriel B.; Loebenberg L.; Walzl G.; Hesseling A.C. (2010)SETTING: The paediatric oncology unit at Tygerberg Children's Hospital, South Africa. OBJECTIVES: To assess the use of the tuberculin skin test (TST) and two commercial interferon-gamma release assays (IGRAs) for the ...
-
Early mortality and loss to follow-up in HIV-infected children starting antiretroviral therapy in Southern Africa
Fenner L.; Brinkhof M.W.G.; Keiser O.; Weigel R.; Cornell M.; Moultrie H.; Prozesky H.; Technau K.; Eley B.; Vaz P.; Pascoe M.; Giddy J.; Van Cutsem G.; Wood R.; Egger M.; Davies M.-A. (2010)Background: Many HIV-infected children in Southern Africa have been started on antiretroviral therapy (ART), but loss to follow up (LTFU) can be substantial. We analyzed mortality in children retained in care and in all ...
-
MRI to demonstrate diagnostic features and complications of TBM not seen with CT
Pienaar M.; Andronikou S.; Van Toorn R. (2009)Background: Computed tomography (CT) findings in children with tuberculous meningitis (TBM) often do not explain the clinical presentation and may even be normal. Magnetic resonance imaging (MRI) has the potential to ...
-
Pyridoxal-5-phosphate plasma concentrations in children receiving tuberculosis chemotherapy including isoniazid
Cilliers K.; Labadarios D.; Schaaf H.S.; Willemse M.; Maritz J.S.; Werely C.J.; Hussey G.; Donald P.R. (2010)Aim: Little is known about pyridoxine nutriture of children treated with isoniazid (INH) regimens. This study documents plasma pyridoxal 5′-phosphate (PLP) concentrations in children, HIV-infected and HIV-uninfected, ...
-
Fine-needle aspiration biopsy: A fi rst-line diagnostic procedure in paediatric tuberculosis suspects with peripheral lymphadenopathy?
Wright C.A.; Hesseling A.C.; Bamford C.; Burgess S.M.; Warren R.; Marais B.J. (2009)OBJECTIVE: To evaluate the diagnostic yield and time to diagnosis of fi ne-needle aspiration biopsy (FNAB) vs. routine respiratory specimens collected from children with a palpable peripheral lymph node mass and symptoms ...
-
Retrospective surveillance of intussusception in South Africa, 1998-2003
Moore S.W.; Kirsten M.; Muller E.W.; Numanoglu A.; Chitnis M.; Le Grange E.; Banieghbal B.; Hadley G.P. (2010)Background. Intussusception is a common gastrointestinal emergency in children and appears to have a somewhat different clinical spectrum in developing countries. Its etiology is still unclear, but a link to infective ...
-
Tuberculous meningitis-related optic neuritis: Recovery of vision with thalidomide in 4 consecutive cases
Schoeman J.F.; Andronikou S.; Stefan D.C.; Freeman N.; Van Toorn R. (2010)Blindness is an uncommon but devastating complication of tuberculosis meningitis. The main causes are chronically raised intracranial pressure (hydrocephalus and/or tuberculomas) or direct involvement of the optic chiasm ...
-
Demyelinating disease of Schilder type in three young South African children: Dramatic response to corticosteroids
Pretorius M.-L.; Loock D.B.; Ravenscroft A.; Schoeman J.F. (1998)Three young children with the Schilder variant of multiple sclerosis were seen within a 3-year period at our hospital. The diagnosis was made on the basis of the typical (but not pathognomonic) clinical and magnetic resonance ...
-
The first 5 years of the family clinic for HIV at Tygerberg hospital: Family demographics, survival of children and early impact of antiretroviral therapy
van Kooten Niekerk N.K.M.; Knies M.M.; Howard J.; Rabie H.; Zeier M.; van Rensburg A.; Frans N.; Schaaf H.S.; Fatti G.; Little F.; Cotton M.F. (2006)Background: Family clinics address the problems of HIV-infected children and their families. The aims were to document demographics of the children and caregivers attending the Family Clinic for HIV at Tygerberg Academic ...
-
Current evaluation of cardiac stab wounds
Harris D.G.; Papagiannopoulos K.A.; Pretorius J.; Van Rooyen T.; Rossouw G.J. (1999)Background. Patients with penetrating cardiac injuries may be stable or only mildly shocked, especially if the laceration has sealed off and the patient has been aggressively resuscitated. Clinical signs, chest roentgenograms, ...
-
Use of the Hereford Parent Attitude Survey as an outcome measure in parent education research.
Brand H.J.; Ellis E.G. (1991)Research on outcome evaluation published since 1980 on the Hereford Parent Attitude Survey was reviewed in terms of sample size, type of parent training program used, and the scales' sensitivity to change in parental ...
-
Perceived parental inconsistency as a factor in the emotional development of behaviour-disordered children
Brand H.J.; Crous B.H.; Hanekom J.D.M. (1990)55 English-speaking institutionalized adolescents (37 boys and 18 girls between ages of 14 and 19 yr.) were given questionnaires measuring perceived parental inconsistency and different components of emotional development. ...
-
Antiretroviral treatment for children with peripartum nevirapine exposure
Palumbo, P.; Lindsey, J. C.; Hughes, M. D.; Cotton, M. F.; Bobat, R.; Meyers, T.; Bwakura-Dangarembizi, M.; Chi, B. H.; Musoke, P.; Kamthunzi, P.; Schimana, W.; Purdue, L.; Eshleman, S. H.; Abrams, E. J.; Millar, L.; Petzold, E.; Mofenson, L. M.; Jean-Philippe, P.; Violari A. (2010)Background: Single-dose nevirapine is the cornerstone of the regimen for prevention of mother-to-child transmission of human immunodeficiency virus (HIV) in resource-limited settings, but nevirapine frequently selects for ...