Chromosome studies in 496 infertile males with a sperm count below 10 million/ml

Date
1984
Authors
Retief A.E.
Van Zyl J.A.
Menkveld R.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Chromosome studies were performed on 106 men with azoospermia and 390 men with oligozoospermia (consistent sperm count below 10 million/ml). Constitutional chromosome abnormalities were found in 14.1% of the azoospermia group and in 5.1% of the oligozoospermia group. An overall incidence of 7.1% constitutional abnormalities indicates that this criterion of selection may be advisable for routine chromosome analysis of infertile men. A reduction of 25% in the workload increases the yield of chromosome abnormalities in the group of infertile men to 10-14 times above that expected in the normal population.
Description
Keywords
aneuploidy, azoospermia, chromosome translocation, diagnosis, etiology, heredity, histology, human, major clinical study, male genital system, male infertility, oligospermia, sex chromosome aberration, Chromosome Aberrations, Chromosome Disorders, Comparative Study, Human, Karyotyping, Male, Oligospermia, Sex Chromosome Aberrations, Sperm Count
Citation
Human Genetics
66
2-3