Anaphylaxis in the paediatric intensive care unit

Date
2008
Authors
Kling S.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Anaphylaxis is uncommonly seen in the paediatric intensive care unit (PICU). Two circumstances under which anaphylaxis could be encountered in the PICU are when a child is admitted for intensive care after an anaphylactic reaction or when a patient in the PICU develops an anaphylactic reaction to his/her therapy. Refractory airway obstruction or refractory hypotension after anaphylaxis are indications for intensive care. The most common causes of anaphylaxis in the PICU are drugs, with antibiotics, anaesthetic agents and muscle relaxants most commonly involved. Anaphylaxis does occur in infants, even as young as 1 month of age, and may be difficult to recognise. Anaphylaxis has even been postulated as an aetiological factor in sudden infant death syndrome (SIDS). The case of a 6-day-old preterm baby who presented with symptoms and signs suggestive of anaphylaxis, but without an obvious trigger is discussed.
Description
Keywords
adrenalin, aminophylline, barbituric acid derivative, beta 2 adrenergic receptor stimulating agent, beta adrenergic receptor blocking agent, beta lactam antibiotic, cephalosporin derivative, cimetidine, cisatracurium, dextran, dopamine, gentamicin, glucagon, halothane, hetastarch, hydrocortisone, ipratropium bromide, local anesthetic agent, muscle relaxant agent, penicillin G, poractant, promethazine, propofol, ranitidine, salbutamol, steroid, theophylline, thiopental, airway obstruction, anaphylaxis, article, asthma, bronchospasm, continuous infusion, eczema, human, hypotension, intensive care unit, loading drug dose, mortality, peanut allergy, prematurity, sudden infant death syndrome
Citation
Current Allergy and Clinical Immunology
21
4