Pseudohyponatraemia in a patient with obstructive jaundice

Le Riche M. ; Burgess L.J. ; Marais A.D. (2006)

Article

Introduction: Pseudohyponatraemia is uncommonly associated with severe hypercholesterolaemia. Severe hypercholesterolaemia encountered in obstructive jaundice due to an abnormal lipoprotein, lipoprotein X (LpX), may result in pseudohyponatraemia. Case report: We report a case of falsely low sodium measurements in a patient with severe hypercholesterolaemia due to obstructive liver disease. The pathophysiology, complications and analytical effects of LpX are briefly discussed. Conclusion: The possibility of pseudohyponatraemia should be considered in severely hypercholesterolaemic samples.

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