The mid dermis graft. An experimental study

Malherbe W.D.F. ; Van Der Walt J.J. (1973)

It is possible in the baboon and also in the human not only to transplant a thin split thickness graft successfully, but to cut a second layer from the donor area and to transplant this mid dermis graft successfully as well. Within one week a new cover of epidermis regenerates on the mid dermis graft from epithelial elements present in the graft. The donor area still contains sufficient epithelial structures to provide its own epidermal cover. At least two grafts can therefore be taken from the same donor area by means of an electric dermatome without any adverse effect on the healing of the donor area, and both these grafts will 'take'. Clinically this means that the available donor skin can theoretically be doubled. Histologically this graft provides a new method of studying the regeneration of epithelium and the process of distribution of melanin.

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