A comparative study using prepared and unprepared frozen semen for donor insemination
De Villiers A.
Van Der Merwe J.P.
MetadataShow full item record
Please cite this item using this persistent URLhttp://hdl.handle.net/10019.1/13399
This item appears in the following collection/s
The aim of this study was to compare the efficacy of pericervical insemination with unprepared semen with that of intrauterine insemination with prepared donor semen in a prospective, randomized, crossover clinical trial. Fifty-four subsequent patients who qualified for therapeutic donor insemination were randomized to receive alternately either an intrauterine insemination with thawed frozen donor semen, prepared by double wash and swim-up, or pericervical insemination with unprepared thawed frozen donor semen in subsequent treatment cycles, with each patient serving as her own control. Eleven pregnancies ensued from 54 cycles of intrauterine insemination (20.4% per cycle), and 2 pregnancies ensued from 58 cycles of pericervical insemination (3.4% per cycle, p = .005). Five pregnancies ensued during the first treatment cycle (13.2%), 4 during the second treatment cycle (17.4%), 2 during the third (13.2%), 1 during the fourth (7.1%), and 1 after the fourth treatment cycle (4.8%). The significantly better pregnancy rate from intrauterine insemination with prepared semen supports this treatment option. The decrease in pregnancy rate after the fourth treatment cycle confirms the need for alternative therapy after 4 failed cycles of therapeutic donor insemination.
Showing items related by title, author, creator and subject.
Virtual reality exposure therapy as treatment for pain catastrophizing in fibromyalgia patients : proof-of-concept study (Study protocol) Morris, Linzette D.; Grimmer-Somers, Karen A.; Spottiswoode, Bruce; Louw, Quinette A. (BioMed Central, 2011-04)Abstract. Background. Albeit exercise is currently advocated as one of the most effective management strategies for fibromyalgia syndrome (FMS); the implementation of exercise as a FMS treatment in reality is significantly ...
Gabrielli W.F.; Nogai S.D.; McKenzie J.M.; Cronje S.; Raubenheimer H.G.; Gabrielli W.F.; Nogai S.D.; McKenzie J.M.; Cronje S.; Raubenheimer H.G. (2009)Lithiation of 1-benzyl-1H-tetrazole followed by transmetallation with [AuCl(PPh3)], [Au(C6F5)(tht)] or [AuCl(tht)] (tht = tetrahydrothiophene) and subsequent alkylation afforded cationic 1-benzyl-4-methyl-4,5-dihydro-1H- ...
Lesson study in continuing professional teacher develop-ment: A South African case study [Lesstudie in voortgesette professionele ontwikkeling van onderwysers: 'N Suid-Afrikaanse gevallestudie] Coe K.; Carl A.; Frick L. (2010)The implementation of successful continuing professional teacher development (CPTD) programmes has been a challenge in South Africa since the introduction of Curriculum 2005. Lesson study, a CPTD model introduced in Japan ...