Long-term linezolid treatment in a young child with extensively drug-resistant tuberculosis

Date
2009
Authors
Schaaf H.S.
Willemse M.
Donald P.R.
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Abstract
Treatment of extensively drug-resistant tuberculosis (XDR-TB) is a challenge. We describe a young child with pulmonary XDR-TB who did not respond to an aggressive multidrug-resistant TB treatment regimen, but was cured with linezolid in combination with other reserve antituberculous drugs. No serious adverse events were observed during 19 months of treatment for XDR-TB. Copyright © 2009 by Lippincott Williams & Wilkins.
Description
Keywords
amikacin, capreomycin, clarithromycin, ethambutol, ethionamide, isoniazid, linezolid, ofloxacin, pyrazinamide, pyridoxine, rifampicin, terizidone, absence of side effects, anamnesis, antibiotic resistance, article, bronchoscopy, case report, child, child care, clinical feature, combination chemotherapy, extensively drug resistant tuberculosis, female, human, peripheral neuropathy, preschool child, priority journal, thorax radiography, Acetamides, Antitubercular Agents, Drug Administration Schedule, Drug Resistance, Multiple, Bacterial, Extensively Drug-Resistant Tuberculosis, Female, Humans, Infant, Oxazolidinones, Tuberculosis, Pulmonary
Citation
Pediatric Infectious Disease Journal
28
8