Burkitt's lymphoma : the prevalence of HIV/AIDS and the outcome of treatment
Date
2018
Journal Title
Journal ISSN
Volume Title
Publisher
Health & Medical Publishing Group
Abstract
The prevalence of HIV in Burkitt’s lymphoma (BL) patients and the outcome of treatment in Cameroon were unknown. Records of all patients diagnosed with BL at three Cameroon Baptist Convention hospitals were reviewed to ascertain the recorded HIV status and outcome of treatment. Of 979 patients diagnosed with BL, 717 were tested for HIV and 11 (1.5%) were HIV-positive. Three of eight patients treated with both cyclophosphamide (CPM)-based chemotherapy and antiretrovirals were alive at 62, 96 and 111 months, respectively. The HIV rate was comparable to that of 1% for the general population of children aged <15 years. Low-cost high-frequency CPM was the only available treatment option for BL and was associated with 37.5% long-term survival in a resource-limited setting.
Description
CITATION: Hesseling, P. B. et al. 2018. Burkitt's lymphoma : the prevalence of HIV/AIDS and the outcome of treatment. South African Medical Journal, 108(2):84-85, doi:10.7196/SAMJ.2018.v108i2.12441.
The original publication is available at http://www.samj.org.za
The original publication is available at http://www.samj.org.za
Keywords
Burkitt's lymphoma, HIV infections -- Cameroon, Burkitt's lymphoma -- Treatment
Citation
Hesseling, P. B. et al. 2018. Burkitt's lymphoma : the prevalence of HIV/AIDS and the outcome of treatment. South African Medical Journal, 108(2):84-85, doi:10.7196/SAMJ.2018.v108i2.12441.