First-episode psychosis: An update

Date
2008
Authors
Chiliza B.
Oosthuizen P.
Emsley R.
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Abstract
Interest in the subject of first-episode psychosis has increased considerably in the last two decades. At present, a number of centres around the world focus on early identification and intervention in people with psychotic disorders. Researchers have focused particularly on people who are possibly experiencing the prodromal phase of the illness in the hope that, by instituting appropriate early intervention, the outcome of schizophrenia will be improved. Patients with first-episode psychosis present with different symptom domains that should be taken into account when planning treatment. Most patients initially respond to treatment; however, there is a high rate of relapse within a few years. It is therefore important that we continue to seek improved relapse prevention strategies. There has also been a resurgence of interest in psychosocial risk factors for the development of schizophrenia in the recent literature. We review the literature on first-episode psychosis and highlight the significant findings.
Description
Keywords
dysbindin, haloperidol, neu differentiation factor, neuroleptic agent, olanzapine, perphenazine, quetiapine, risperidone, ziprasidone, acute disease, clinical trial, cognition, cognitive therapy, delusion, depression, diagnostic and statistical manual of mental disorders, disease classification, disease severity, disorientation, drug efficacy, early diagnosis, early intervention, family therapy, group therapy, hallucination, health care planning, human, long term care, low drug dose, mental health care, mood disorder, negative syndrome, positive syndrome, psychosis, quality of life, review, risk factor, schizophrenia, symptomatology, treatment outcome, unspecified side effect
Citation
South African Journal of Psychiatry
14
1