Oligonucleotide (GTG)5 as an epidemiological tool in the study of nontuberculous mycobacteria

Cilliers F.J. ; Warren R.M. ; Hauman J.H. ; Wiid I.J.F. ; Van Helden P.D. (1997)


Analysis of restriction fragment length polymorphisms in the genome of Mycobacterium tuberculosis (DNA fingerprinting) has proved to be a useful epidemiological tool in the study of tuberculosis within populations or communities. However, to date, no similar method has been developed to study the epidemiology of nontuberculous mycobacteria (NTM). In this communication, we report that a simple oligonucleotide repeat, (GTG)5 can be used to accurately genotype all species and strains of NTM tested. We suggest that this technology is an easily applied and accurate tool which can be used for the study of the epidemiology of NTM.

Please refer to this item in SUNScholar by using the following persistent URL: http://hdl.handle.net/10019.1/10142
This item appears in the following collections: