Use of spoligotyping for accurate classification of recurrent tuberculosis
Date
2002
Authors
Warren R.M.
Streicher E.M.
Charalambous S.
Churchyard G.
Van der Spuy G.D.
Grant A.D.
Van Helden P.D.
Victor T.C.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
The spoligotyping method has become an important tool for the tracking of Mycobacterium tuberculosis strains in different epidemiological settings. In this study, we demonstrate the ability of the spoligotyping technique to accurately determine the pathogenetic mechanism of recurrent disease. This methodology has advantages over conventional restriction fragment length polymorphism methods which may be useful in large-scale intervention studies.
Description
Keywords
article, bacterial genetics, bacterium identification, clinical article, disease classification, human, Mycobacterium tuberculosis, nonhuman, priority journal, recurrent infection, restriction fragment length polymorphism, spoligotyping, tuberculosis, Diagnostic Techniques and Procedures, Humans, Mycobacterium tuberculosis, Polymorphism, Restriction Fragment Length, Recurrence, Tuberculosis, Bacteria (microorganisms), Mycobacterium, Mycobacterium tuberculosis
Citation
Journal of Clinical Microbiology
40
10
40
10