Genotypic and Phenotypic Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates from Rural Districts of the Western Cape Province of South Africa

Streicher E.M. ; Warren R.M. ; Kewley C. ; Simpson J. ; Rastogi N. ; Sola C. ; Van Der Spuy G.D. ; Van Helden P.D. ; Victor T.C. (2004)


Genotypic and phenotypic analysis of drug-resistant Mycobacterium tuberculosis isolates from the Western Cape Province of South Africa showed that drug resistance is widespread and recently transmitted. Multidrug-resistant (MDR) isolates comprise 40% of this collection, and a large pool of isoniazid monoresistance may be a future source of MDR tuberculosis.

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