Effect of potentially probiotic lactobacilli on faecal enzyme activity in minipigs on a high-fat, high-cholesterol diet - A preliminary in vivo trial

Date
2003
Authors
Haberer P.
Du Toit M.
Dicks L.M.T.
Ahrens F.
Holzapfel W.H.
Journal Title
Journal ISSN
Volume Title
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Abstract
Minipigs were fed a "Western-style", high-cholesterol diet for a baseline period, followed by the diet containing a mixture of three Lactobacillus strains with potential probiotic features, after which a normal pig diet was followed. The faecal enzyme activity for β-glucuronidase and azoreductase, which are commonly considered as markers for procarcinogenic activity, was significantly reduced during the 5 weeks of "probiotic" supplementation. During the period of Lactobacillus administration, the cell counts for total anaerobes increased, whereas the total number of aerobes showed no change. © 2003 Elsevier Science B.V. All rights reserved.
Description
Keywords
azo reductase, beta glucuronidase, biochemical marker, probiotic agent, aerobic bacterium, anaerobic bacterium, article, bacterial strain, carcinogenic activity, cell count, cholesterol diet, controlled study, diet supplementation, enzyme activity, feces analysis, Lactobacillus johnsonii, Lactobacillus reuteri, nonhuman, swine, Animals, Cholesterol, Dietary, Dietary Fats, Feces, Glucuronidase, Lactobacillus, NADH, NADPH Oxidoreductases, Probiotics, Swine, Swine, Miniature, Lactobacillus, Sus scrofa
Citation
International Journal of Food Microbiology
87
3