Catecholamine release as mediator of intracellular enzyme activation in ischaemic perfused rat hearts

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dc.contributor.authorHough, F. S.
dc.contributor.authorGevers, W.
dc.date.accessioned2011-03-18T14:57:55Z
dc.date.available2011-03-18T14:57:55Z
dc.date.issued1975
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractIsolated rat hearts perfused at suboptimal pressures have been studied as a model for generalized myocardial ischaemia. Glycogen phosphorylase a and hormone sensitive triglyceridase activities, measured as markers for endogenous catecholamine release, were significantly increased at low perfusion pressures. Pharmacological blockage of noradrenaline re uptake accentuated these effects, and depletion of catecholamine reserves eliminated them. This phenomenon may be important in the pathophysiology of cardiac ischaemia and its serious complications.en_ZA
dc.description.versionPublishers' version
dc.format.extentp.538-543 : ill.
dc.identifier.citationHough, F.S. & Gevers, W. 1975. Catecholamine release as mediator of intracellular enzyme activation in ischaemic perfused rat hearts. SA Medical Journal, 49(14), 538-543, http://archive.samj.org.za/
dc.identifier.ismn2078-5135 (online)
dc.identifier.issn0256-9574 (print)
dc.identifier.urihttp://hdl.handle.net/10019.1/7743
dc.language.isoen_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)
dc.rights.holderHealth and Medical Publishing Group (HMPG)
dc.subjectMyocardial ischaemiaen_ZA
dc.subjectCatecholamine releaseen_ZA
dc.titleCatecholamine release as mediator of intracellular enzyme activation in ischaemic perfused rat heartsen_ZA
dc.typeArticle
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