Valvular heart disease associated with systemic lupus erythematosus - The tygerberg hospital experience

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dc.contributor.authorPont K.
dc.contributor.authorPretorius M.M.
dc.contributor.authorDoubell A.F.
dc.contributor.authorReuter H.
dc.date.accessioned2011-05-15T16:15:58Z
dc.date.available2011-05-15T16:15:58Z
dc.date.issued2000
dc.description.abstractBackground. Valvular heart disease is the most important cardiac manifestation of systemic lupus erythematosus (SLE). We performed a study to determine the presence of valvular heart disease in our patients with SLE. Methods. We performed clinical, electrocardiographic, transthoracic echocardiographic and laboratory evaluations in 24 patients with SLE. The echocardiographic findings were compared with those of 10 age- and sex-matched volunteers. Results. None of the 24 patients had obvious symptoms of cardiac origin. Valvular abnormalities were common. Valvular thickening was the most predominant finding (more than 50%), followed by mitral valvular regurgitation (12.5%) and pericardial effusions (12.5%). Valvular abnormalities were uncommon in the control group. Conclusion. Valvular heart disease is common in our patient population with SLE, although haemodynamically significant valvular dysfunction is rare.
dc.description.versionArticle
dc.identifier.citationCardiovascular Journal of Southern Africa
dc.identifier.citation11
dc.identifier.citation3
dc.identifier.issn10159657
dc.identifier.urihttp://hdl.handle.net/10019.1/13573
dc.subjectadolescent
dc.subjectadult
dc.subjectarticle
dc.subjectclinical article
dc.subjectclinical feature
dc.subjectcontrolled study
dc.subjectdiagnostic procedure
dc.subjectelectrocardiography
dc.subjectfemale
dc.subjecthemodynamics
dc.subjecthuman
dc.subjectlaboratory diagnosis
dc.subjectmale
dc.subjectmitral valve regurgitation
dc.subjectpericardial effusion
dc.subjectsystemic lupus erythematosus
dc.subjecttransthoracic echocardiography
dc.subjectvalvular heart disease
dc.titleValvular heart disease associated with systemic lupus erythematosus - The tygerberg hospital experience
dc.typeArticle
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