Evidence of co and triple infections of Hepatitis B and C amongst HIV infected pregnant women in Buea, Cameroon
Date
2016-03
Journal Title
Journal ISSN
Volume Title
Publisher
Science Publishing Group
Abstract
Little epidermiological data is available on the prevalence of HIV, Hepatitis B and C, Co-and or triple infection
during pregnancy in Cameroon as well as many other resource limited settings. HIV and Hepatitis B and C are major public
health concerns world wide. Our study aimed at assessing the seroprevalence of Hepatitis B and C amongst HIV infected
pregnant women in Buea, located in the Southwest region of Cameroon. A Cross-sectional study on consented pregnant
women were conducted from March 2015 to August 2015. HIV-1 infections were detected using the national HIV-1 test
algorithms. Hepatitis B surface antigen (HBsAg), anti-HBe and anti- Hepatitis C (anti-HCV) were detected using Enzyme
linked Immunosorbent Assays (ELISAs). Of the 1230 recruited pregnant women, 97/1230 (7.8%) (95% CI: 3.5, 29.0%) were
confirmed HIV-1 positive. HIV/HBV co-infection were observed in 14/97 (14.4%) (95% CI: 39.8, 100%), whilst 11/97
(11.3 %; 95% CI: 27.5, 100%) were HIV/HCV co-infections. Two HIV-infected pregnant women (8/97(8.2%; 95% CI: 0.1,
17.2%)) were HIV/HBV/HCV triple-infected. Anti-HBc was detected in all HBV-infected pregnant women (14/14; (100.0%))
(95.0% CI: 39.8, 100.0%). Seropositivity for HIV-1 was higher (37%) amongst subjects aged between 32-37 years, whilst none
was found above 40. From our results we conclude that Co- and triple infections of HIV, Hepatitis B and C were present
amongst pregnant women in Buea. Epidemiological data generated from this study are limited due to the existence of triple
infected. It will therefore serve as a guide to the government policies to reinforce screening, treatment and prevention
strategies, through its Mother–to-Child–transmission (pMTCT) Programme nationwide.
Description
CITATION: Ikomey, G. M. et al. 2016. Evidence of co and triple infections of Hepatitis B and C amongst HIV infected pregnant women in Buea, Cameroon. Science Journal of Public Health, 4(2):127-131, doi:10.11648/j.sjph.20160402.17.
The original publication is available at http://www.sciencepublishinggroup.com/journal/index?journalid=251
The original publication is available at http://www.sciencepublishinggroup.com/journal/index?journalid=251
Keywords
Hepatitis B -- Cameroon -- Buea, HIV infections -- Cameroon -- Buea, Hepatitis C -- Cameroon -- Buea, Pregnant women -- Cameroon -- Buea
Citation
Ikomey, G. M. et al. 2016. Evidence of co and triple infections of Hepatitis B and C amongst HIV infected pregnant women in Buea, Cameroon. Science Journal of Public Health, 4(2):127-131, doi:10.11648/j.sjph.20160402.17.