Home-based treatment of childhood neurotuberculosis

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dc.contributor.authorSchoeman J.
dc.contributor.authorMalan G.
dc.contributor.authorvan toorn R.
dc.contributor.authorSpringer P.
dc.contributor.authorParker F.
dc.contributor.authorBooysen J.
dc.date.accessioned2011-05-15T16:02:03Z
dc.date.available2011-05-15T16:02:03Z
dc.date.issued2009
dc.description.abstractIntroduction: In-hospital treatment is widely recognized as the gold standard of treatment for children with neurotuberculosis due to the complexity of care and serious consequences of non-compliance. The continuous rise in the incidence of tuberculosis (TB), fuelled by an HIV-pandemic, has resulted in severe bed shortages in tertiary, secondary and TB hospitals in the Western Cape. Objective: To evaluate the feasibility of home-based directly observed therapy (DOT) in TBM. Method: Suitability screening by social workers, in-hospital monitoring of mother-child interaction, medication side effects and intolerance followed by a supervised outpatient surveillance program. Results: Forty of the 52 children screened were approved for home-based treatment. Thirty-four of these 40 patients (85%) completed TBM treatment successfully at home, and no patient defaulted treatment. Conclusion: Home-based treatment of childhood neurotuberculosis is feasible in selected patients under close supervision. Mothers could be considered as primary DOT supporters. © The Author [2008]. Published by Oxford University Press. All rights reserved.
dc.description.versionArticle
dc.identifier.citationJournal of Tropical Pediatrics
dc.identifier.citation55
dc.identifier.citation3
dc.identifier.issn1426338
dc.identifier.other10.1093/tropej/fmn097
dc.identifier.urihttp://hdl.handle.net/10019.1/12285
dc.subjectethambutol
dc.subjectethionamide
dc.subjectisoniazid
dc.subjectprednisone
dc.subjectpyrazinamide
dc.subjectrifampicin
dc.subjecttuberculostatic agent
dc.subjectadolescent
dc.subjectarticle
dc.subjectcaregiver support
dc.subjectcentral nervous system tuberculosis
dc.subjectchild
dc.subjectclinical article
dc.subjectdirectly observed therapy
dc.subjectdrug substitution
dc.subjectdrug withdrawal
dc.subjectevening dosage
dc.subjectfeasibility study
dc.subjectfemale
dc.subjecthome based directly observed therapy
dc.subjecthome care
dc.subjecthospital readmission
dc.subjecthuman
dc.subjectmale
dc.subjectmorning dosage
dc.subjectmother child relation
dc.subjectnausea and vomiting
dc.subjectoutcome assessment
dc.subjectpatient compliance
dc.subjectpatient selection
dc.subjectsurvivor
dc.subjecttreatment response
dc.subjectvomiting
dc.subjectAdolescent
dc.subjectAntitubercular Agents
dc.subjectChild
dc.subjectChild, Preschool
dc.subjectCommunity Health Services
dc.subjectDirectly Observed Therapy
dc.subjectFemale
dc.subjectHome Care Services
dc.subjectHouse Calls
dc.subjectHumans
dc.subjectMale
dc.subjectMothers
dc.subjectPatient Compliance
dc.subjectTreatment Outcome
dc.subjectTuberculosis, Central Nervous System
dc.titleHome-based treatment of childhood neurotuberculosis
dc.typeArticle
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