Combination of radiosensitizers and hyperthermia in tumour radiotherapy

dc.contributor.authorBrueckner, V.
dc.date.accessioned2011-03-18T14:59:49Z
dc.date.available2011-03-18T14:59:49Z
dc.date.issued1981
dc.descriptionReview
dc.description.abstractSpecific metabolic properties of hypoxic (and therefore radio-resistant) tumour cells are responsible for the selective effect of radiosensitizers (such as misonidazole) and hyperthermia upon these cells in respect of radiosensitization as well as cytotoxicity. Radiosensitizers and hyperthermia should therefore be used to improve the results of tumour radiotherapy; enhancement ratios of 2-4 have already been attained experimentally with this combined treatment. In spite of these good results, certain problems exist, and up to now the combination of radiosensitizers and hyperthermia has not been used to any great extent for tumours in humans.en_ZA
dc.format.extentp. 116-118
dc.identifier.urihttp://hdl.handle.net/10019.1/8078
dc.subjectCander -- Thermotherapyen_ZA
dc.subjectCancer -- Radiotherapyen_ZA
dc.subjectRadiation-sensitizing agentsen_ZA
dc.titleCombination of radiosensitizers and hyperthermia in tumour radiotherapyen_ZA
dc.typeReview
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