The effect of clomiphene and conjugated oestrogens on cervical mucus
Date
1981-08
Authors
Van der Merwe J. V.
Journal Title
Journal ISSN
Volume Title
Publisher
HMPG
Abstract
The analysis of 157 menstrual cycles in 50 patients on ovulation-induced regimens showed that in restoring ovulation clomiphene citrate inhibited cervical mucus production and caused hypersecretion of oestradiol. The inhibitory effect was inversely proportional to serum oestradiol levels, and the addition of conjugated oestrogens did not rectify the inhibitory effect, increase plasma oestradiol levels or increase cycle length. Doubling the clomiphene dosage made no significant difference to any of the parameters examined. The mechanism of this inhibitory effect is still obscure.
Description
Keywords
Cervical mucus, Menstrual cycle
Citation
Van der Merwe, J.V. 1981. The effect of clomiphene and conjugated oestrogens on cervical mucus. SA Medical Journal, 29 August: 347-349.