The characterisation of candida isolates from the oral cavities of a group of acute leukemia patients
Date
1997-12
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Stellenbosch : Stellenbosch University
Abstract
AFRIKAANSE OPSOMMING: Die doel van hierdie studie was om die invloed van chemoterapie en antifungale terapie op Candida spesies in die mondholte van 29 leukemie pasiënte te ondersoek. Smere en mondspoele was geneem van die pasiënte. Candida isolate was op Sabouraud dekstrose agar sowel as differensiële media gekweek. Isolate was geïdentifiseer met behulp van fenotipiese eienskappe asook koolhidraat assimilasie profiele. Genotipering van C. albicans stamme was gedoen met behulp van die C. albicans spesie-spesifieke peiler, Ca3.
ENGLISH ABSTRACT: The aim of study was to investigate the effect of cytotoxic therapy and prolonged antifungal therapy on oral Candida species in a group of 29 acute leukemia patients. THe presence of oral lesions was noted, and smears saline rinses were collected from the oral cavaties of the patients. Candida isolates were grown on Sabouraud dextrose agar and differential media. Isolates were identified with the aid of phenotypical characteristics and sugar assimilation profiles. C. albicans strains were genotyped with the C. albicans species-specific probe, Ca3.
ENGLISH ABSTRACT: The aim of study was to investigate the effect of cytotoxic therapy and prolonged antifungal therapy on oral Candida species in a group of 29 acute leukemia patients. THe presence of oral lesions was noted, and smears saline rinses were collected from the oral cavaties of the patients. Candida isolates were grown on Sabouraud dextrose agar and differential media. Isolates were identified with the aid of phenotypical characteristics and sugar assimilation profiles. C. albicans strains were genotyped with the C. albicans species-specific probe, Ca3.
Description
Thesis (MSc)--University of Stellenbosch, 1997.
Keywords
Thrush (Mouth disease), Thrush (Mouth disease) -- Treatment, Leukemia -- Chemotherapy -- Complications -- Treatment