Treatment of Sydenham chorea with intravenous immunoglobulin

Date
2012
Authors
Walker K.
Brink A.
Lawrenson J.
Mathiassen W.
Wilmshurst J.M.
Journal Title
Journal ISSN
Volume Title
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Abstract
Sydenham chorea is a post-streptococcal, autoimmune, neuropsychiatric, movement disorder. There is no effective treatment. In a randomized study, comparison was made of the outcomes of 10 children treated with standard management alone compared to 10 who received additional intravenous immunoglobulin. The outcomes were assessed using a clinical rating scale, brain single-photon emission computed tomography, and the duration of symptomatic treatment. All three outcome measurement tools found improved outcomes in the group that received intravenous immunoglobulin. © SAGE Publications 2012.
Description
Keywords
clinical rating scale, immunomodulatory therapy, single-photon emission computed tomography, Sydenham chorea
Citation
Journal of Child Neurology
27
2
147
155