Tuberculosis and HIV - Features of the co-infection [TB und HIV-Besonderheiten der Ko-infektion]

Date
2011
Authors
Luthi B.
Diacon A.H.
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Volume Title
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Abstract
The human immunodeficiency virus (HIV) epidemic has allowed the incidence of tuberculosis to rise globally and particularly in sub-Saharan Africa. Diagnosis and treatment of tuberculosis is more complex in patients with HIV/AIDS. Sputum smear microscopy is performing poorly in HIV-infected individuals, who are often started on antituberculosis treatment on clinical grounds. The treatment of coinfected patients requires antituberculosis and antiretroviral drugs to be administered concomittantly; challenges include pill burden and patient compliance, drug interactions, overlapping toxic effects, and immune reconstitution inflammatory syndrome. Current guidelines recommend starting antiretroviral treatment within a few weeks of antituberculosis therapy for patients with CD4 cell counts < 350 cells/μl. © 2011 by Verlag Hans Huber, Hogrefe AG, Bern.
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Citation
Therapeutische Umschau
68
7
http://www.scopus.com/inward/record.url?eid=2-s2.0-79960066457&partnerID=40&md5=2300e0f3290d127bff90448af4a0f83f
URI
http://hdl.handle.net/10019.1/17221
Collections
Stellenbosch University - Scopus Publications