Pigmenting pityriasis alba
Date
1993
Authors
Du Toit M.J.
Jordaan H.F.
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Abstract
We conducted a prospective study of 20 patients with pigmenting pityriasis alba (PPA) over a period of two years. Characteristic morphology revealed a central zone of bluish hyperpigmentation surrounded by a hypopigmented, slightly scaly halo of variable width. All patients displayed lesions on the face. Concomitant extrafacial involvement was uncommon. A significant finding was an associated dermatophyte infection in 13 patients (65%). These patients all received griseofulvin 10 mg/kg/day for eight weeks, resulting in the resolution of PPA in seven within 4 to 20 weeks. These were also treated with 1% hydrocortisone. Biopsy specimens from two patients showed similar features, namely, a subacute dermatitis with variable pigment incontinence. Immunohistochemical labeling revealed a preponderance of T lymphocytes. Pigmenting pityriasis alba seems to be a variant of classic pityriasis alba showing a strong association with dermatophyte infection, especially tinea capitis. It may be related to lichenoid melanodermatitis.
Description
Keywords
antifungal agent, griseofulvin, hydrocortisone, pigment, adolescent, adult, article, child, clinical article, clinical feature, dermatitis, dermatomycosis, dermatophyte, disease association, erythematosquamous skin disease, face, female, human, human tissue, hyperpigmentation, hypopigmentation, immunohistochemistry, incontinentia pigmenti, male, morphology, preschool child, prospective study, school child, skin biopsy, skin pigmentation, t lymphocyte, tinea capitis, Adolescent, Adult, Child, Child, Preschool, Dermatitis, Atopic, Dermatomycoses, Female, Follow-Up Studies, Griseofulvin, Human, Hydrocortisone, Topical, Immunoglobulin E, Male, Pigmentation Disorders, Pityriasis, Prospective Studies, Skin
Citation
Pediatric Dermatology
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