Shigellosis in the south-western Cape of Good Hope 1968-85

Date
1987
Authors
Donald P.R.
Pretorius M.-L.
Burger P.J.
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Abstract
During the period 1968-85 shigella organisms were isolated from stool specimens of 1562 patients attending Tygerberg Hospital, situated in the south-western province of the Cape of Good Hope of the Republic of South Africa. Shigella flexneri (72% of patients) was the commonest subgroup identified. Sh. sonnei was the second-commonest isolate (20%), with smaller numbers of Sh. boydii (5%) and Sh. dysenteriae (3%). Sh. dysenteriae has not been isolated since 1979. In 1985 30% of isolates were resistant to ampicillin and 52% to trimethroprim-sulphamethoxazole. During this period 12 cases of shigellaemia were seen, 11 in young infants less than 13 months of age who were malnourished in 6 cases. The single adult had had a previous gastrectomy and splenectomy.
Description
Keywords
ampicillin, antibiotic agent, sulfamethoxazole, trimethoprim, adult, antibiotic resistance, chemotherapy, child, digestive system, drug resistance, geographic distribution, human, large intestine, shigella, shigella dysenteriae, shigella flexneri, shigella sonnei, shigellosis, short survey, south africa, therapy, Drug Resistance, Microbial, Dysentery, Bacillary, Feces, Female, Human, Infant, Male, Middle Age, Seasons, Serotyping, Shigella, South Africa
Citation
Epidemiology and Infection
98
2