Inhibition of bovine serum amine oxidase activity by aminoalkyl-aminoanthraquinones
Date
1988
Authors
Shephard G.S.
Katzhendler J.
Gean K.F.
Kreisel M.
Bachrach U.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
In this study we tested the effect of various aminoalkyl-aminoanthraquinones on the activity of polyamine oxidizing enzymes. It will be shown that the oxidation of the polyamines spermidine and spermine is dramatically inhibited by these compounds.
Description
Keywords
amine oxidase (flavin containing), aminoalkylaminoanthraquinone derivative, kidney enzyme, putrescine, spermidine, spermine, unclassified drug, animal cell, cattle, enzyme blood level, enzyme inhibition, nonhuman, priority journal, swine, Amine Oxidoreductases, Animal, Anthraquinones, Cattle, Kinetics, Spermidine, Spermine, Structure-Activity Relationship, Support, Non-U.S. Gov't
Citation
Biochemical Pharmacology
37
24
37
24