Change in co-receptor usage of current South African HIV-1 subtype C primary isolates
Date
2002
Authors
Van Rensburg E.J.
Smith T.-L.
Zeier M.
Robson B.
Sampson C.
Treurnicht F.
Engelbrecht S.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Phenotypic analysis was performed on 13 HIV-1 strains isolated between 2000 and 2001. Syncytium-inducing and non-syncytium-inducing subtype C viruses were found, most of which used more than one co-receptor. For the first time subtype B viruses were isolated from South African heterosexual patients, a subtype previously associated only with homosexual spread in this geographical region.
Description
Keywords
article, geographic distribution, heterosexuality, homosexuality, Human immunodeficiency virus 1, phenotype, priority journal, syncytium, virus isolation, virus strain, virus typing, Cell Line, Female, Heterosexuality, HIV Infections, HIV-1, Homosexuality, Male, Humans, Male, Phenotype, Receptors, CCR5, Receptors, CXCR4, South Africa
Citation
AIDS
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