One-pot preparation of coenzyme a analogues via an improved chemo-enzymatic synthesis of pre-CoA thioester synthons
Date
2007
Authors
Van Wyk M.
Strauss E.
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
Coenzyme A analogues are synthesized in a one-pot preparation by biotransformation of pantothenate thioesters through the simultaneous use of three CoA biosynthetic enzymes, followed by aminolysis. © The Royal Society of Chemistry.
Description
Keywords
thioester, aminolysis, article, biotransformation, chemical procedures, reaction analysis, synthesis, Amines, Chromatography, High Pressure Liquid, Coenzyme A, Deamination, Escherichia coli, Esters, Kinetics, Molecular Structure, Staphylococcus aureus, Sulfhydryl Compounds
Citation
Chemical Communications
4
4