Browsing by Author "Hewlett, R. H."
Now showing 1 - 1 of 1
Results Per Page
Sort Options
- ItemA study of a family with inherited disease of cardiac and skeletal muscle. Part II. Skeletal muscle morphology and mitochondrial oxidative phosphorylation(Health and Medical Publishing Group -- HMPG, 1981-03) Lochner, A.; Hewlett, R. H.; O'Kennedy, A.; Van der Walt, J. J.; Tiedt, F. A. C.; Hoffman, H.; De Graaf, A. S.; Przybojewski, J. Z.; Torrington, M.Skeletal muscle morphology and mitochondrial oxidative phosphorylation capacity were examined in a family whose members showed varying combinations of mental subnormality, cardiomyopathy and muscle weakness. Light and electron microscopic findings suggested a neuropathic process, while tests of mitochondrial function indicated a state of tight coupling of oxidative phosphorylation, a feature in marked contrast to those in biochemical studies so far reported.