Carbapenemase-producing Enterobacteriaceae colonisation in adult inpatients : a point prevalence study
Date
2019
Journal Title
Journal ISSN
Volume Title
Publisher
AOSIS
Abstract
Background: Infections caused by carbapenemase-producing Enterobacteriaceae (CPE) have been increasing worldwide in recent years, but data regarding the prevalence and clinical significance of CPE colonisation in South Africa is not well documented. Local private hospital groups have implemented routine screening programmes for selected high-risk patients as endorsed by the South African Society for Clinical Microbiology. This practice is not routinely performed in the public sector.
Methods: A point prevalence study was performed at Tygerberg Hospital (TBH) by screening patients of all the adult inpatient wards to investigate the current prevalence of CPE colonisation. Common risk factors associated with CPE colonisation were also investigated.
Results: From a total of 439 patient samples collected, only one patient was colonised with a Klebsiella pneumoniae organism harbouring blaNDM-1. The identified patient had none of the common risk factors associated with CPE colonisation.
Conclusion: Based on these findings, screening for CPE colonisation in adults on admission to TBH is currently not recommended.
Description
CITATION: Nel, P., Paterson, L. A. & Hoffmann, R. 2019. Carbapenemase-producing Enterobacteriaceae colonisation in adult inpatients : a point prevalence study. Southern African Journal of Infectious Diseases, 34(1):a129, doi:10.4102/sajid.v34i1.129.
The original publication is available at https://sajid.co.za
The original publication is available at https://sajid.co.za
Keywords
CPE colonisation., Carbapenemase, Enterobacteriaceae, Klebsiella pneumoniae
Citation
Nel, P., Paterson, L. A. & Hoffmann, R. 2019. Carbapenemase-producing Enterobacteriaceae colonisation in adult inpatients : a point prevalence study. Southern African Journal of Infectious Diseases, 34(1):a129, doi:10.4102/sajid.v34i1.129