Endopap®- versus Pipelle®-sampling in the diagnosis of postmenopausal endometrial disease

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dc.contributor.authorVan Den Bosch T.
dc.contributor.authorVandendael A.
dc.contributor.authorWranz P.A.B.
dc.contributor.authorLombard C.J.
dc.date.accessioned2011-05-15T16:16:22Z
dc.date.available2011-05-15T16:16:22Z
dc.date.issued1996
dc.description.abstractObjective: To evaluate the accuracy of Endopap®- and Pipelle®-sampling in the diagnosis of postmenopausal disease. Study Design: Observational study in the setting of a University Hospital. One hundred and six consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytology underwent an Endopap® sampling as well as a Pipelle® biopsy. Thereafter, 89 of those women underwent a hysteroscopy and curettage (n = 71) or a hysterectomy (n = 18). The diagnostic accuracy of Pipelle® and Endopap® was assessed against the final diagnosis. Results: Endometrial carcinoma was found in five cases (6%), benign disease in 34 (38%). The sensitivity of Endopap® and Pipelle® for the detection of endometrial disease was 56 and 51%, respectively, with a specificity of 94 and 100%, respectively. The sensitivity for endometrial carcinoma was 80% for Endopap® and 100% for Pipelle®. Conclusion: Our data tend to favor Pipelle® against Endopap® as diagnostic tool in endometrial disease in symptomatic postmenopausal women.
dc.description.versionArticle
dc.identifier.citationEuropean Journal of Obstetrics Gynecology and Reproductive Biology
dc.identifier.citation64
dc.identifier.citation1
dc.identifier.issn03012115
dc.identifier.other10.1016/0301-2115(95)02274-0
dc.identifier.urihttp://hdl.handle.net/10019.1/13749
dc.subjectadult
dc.subjectarticle
dc.subjectcancer diagnosis
dc.subjectclinical trial
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectdiagnostic accuracy
dc.subjectendometriosis
dc.subjectendometrium carcinoma
dc.subjectfemale
dc.subjecthuman
dc.subjecthuman tissue
dc.subjectmajor clinical study
dc.subjectpostmenopause
dc.subjectpriority journal
dc.subjectsampling
dc.subjectbiopsy
dc.subjectcomparative study
dc.subjectdifferential diagnosis
dc.subjectendometrium
dc.subjectendometrium tumor
dc.subjectinstrumentation
dc.subjectpathology
dc.subjectsensitivity and specificity
dc.subjectuterus bleeding
dc.subjectuterus disease
dc.subjectBiopsy
dc.subjectDiagnosis, Differential
dc.subjectEndometrial Neoplasms
dc.subjectEndometrium
dc.subjectFemale
dc.subjectHumans
dc.subjectPostmenopause
dc.subjectSensitivity and Specificity
dc.subjectUterine Diseases
dc.subjectUterine Hemorrhage
dc.titleEndopap®- versus Pipelle®-sampling in the diagnosis of postmenopausal endometrial disease
dc.typeArticle
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