Prediction of functional reserves after lung resection: Comparison between quantitative computed tomography, scintigraphy, and anatomy

Simple item page
dc.contributor.authorBolliger C.T.
dc.contributor.authorGuckel C.
dc.contributor.authorEngel H.
dc.contributor.authorStohr S.
dc.contributor.authorWyser C.P.
dc.contributor.authorSchoetzau A.
dc.contributor.authorHabicht J.
dc.contributor.authorSoler M.
dc.contributor.authorTamm M.
dc.contributor.authorPerruchoud A.P.
dc.date.accessioned2011-05-15T15:57:32Z
dc.date.available2011-05-15T15:57:32Z
dc.date.issued2002
dc.description.abstractBackground and Objectives: We prospectively compared five techniques to estimate predicted postoperative function (ppo F) after lung resection: recently proposed quantitative CT scans (CT), perfusion scans (Q), and three anatomical formulae based on the number of segments (S), functional segments (FS), and subsegments (SS) to be removed. Methods: Four parameters were assessed: FEV1, FVC, DLCO and VO2max, measured preoperatively and 6 months postoperatively in 44 patients undergoing pulmonary resection, comparing their ppo value to the postoperatively measured value. Results: The correlations (r) obtained with the five methods were for CT: FEV1 = 0.91, FVC = 0.86, DLCO = 0.84, VO2max = 0.77; for Q: 0.92, 0.90, 0.85, 0.85; for S: 0.88, 0.86, 0.84, 0.75; for FS: 0.88, 0.85, 0.85, 0.75, and for SS: 0.88, 0.86, 0.85, 0.75, respectively. The mean difference between ppo values and postoperatively measured values was smallest for Q estimates and largest for anatomical estimates using S. Stratification of the extent of resection into lobectomy (n = 30) + wedge resections (n = 4) versus pneumonectomy (n = 10) resulted in persistently high correlations for Q and CT estimates, whereas all anatomical correlations were lower after pneumonectomy. Conclusions: We conclude that both Q- and CT-based predictions of postoperative cardiopulmonary function are useful irrespective of the extent of resection, but Q-based results were the most accurate. Anatomically based calculations of ppo F using FS or SS should be reserved for resections not exceeding one lobe. Copyright © 2002 S. Karger AG, Basel.
dc.description.versionArticle
dc.identifier.citationRespiration
dc.identifier.citation69
dc.identifier.citation6
dc.identifier.issn257931
dc.identifier.other10.1159/000066474
dc.identifier.urihttp://hdl.handle.net/10019.1/10461
dc.subjectaccuracy
dc.subjectadult
dc.subjectaged
dc.subjectanatomy
dc.subjectarticle
dc.subjectclinical article
dc.subjectclinical trial
dc.subjectcomputer assisted tomography
dc.subjectcontrolled clinical trial
dc.subjectcontrolled study
dc.subjectcorrelation analysis
dc.subjectfemale
dc.subjectforced expiratory volume
dc.subjecthuman
dc.subjectintermethod comparison
dc.subjectlobectomy
dc.subjectlung function
dc.subjectlung resection
dc.subjectmale
dc.subjectprediction
dc.subjectpriority journal
dc.subjectquantitative analysis
dc.subjectscintigraphy
dc.subjectAged
dc.subjectFemale
dc.subjectForced Expiratory Volume
dc.subjectHumans
dc.subjectLung
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectOxygen Consumption
dc.subjectPneumonectomy
dc.subjectPostoperative Period
dc.subjectProspective Studies
dc.subjectRespiratory Function Tests
dc.subjectSpirometry
dc.subjectTomography, X-Ray Computed
dc.subjectVital Capacity
dc.titlePrediction of functional reserves after lung resection: Comparison between quantitative computed tomography, scintigraphy, and anatomy
dc.typeArticle
Files
Collections
Stellenbosch University - Scopus Publications