Cerebrospinal fluid lactate and lactate dehydrogenase levels as diagnostic aids in tuberculous meningitis

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dc.contributor.authorDonald P. R.
dc.contributor.authorMalan C.
dc.date.accessioned2011-03-18T14:59:44Z
dc.date.available2011-03-18T14:59:44Z
dc.date.issued1985
dc.descriptionArticle
dc.descriptionThe original publication is available at http://www.samj.org.za
dc.description.abstractThe value of cerebrospinal fluid (CSF) lactate and lactate dehydrogenase (LD) values as aids in differentiating tuberculous meningitis (TBM) from aseptic meningitis has been investigated. Using an upper limit of normal for CSF lactate levels of 2.75 mmol/l resulted in detection of 24 out of 26 cases of TBM (a sensitivity of 92%). If, however, a level of 3.85 mmol/l was taken as the upper limit of normal, then 18 out of 26 cases were detected (a sensitivity of 69%). Using 40 U/l as the upper limit of normal for LD levels detected 21 out of 38 cases of TBM (a sensitivity of 55%). Both tests may give normal values in the presence of TBM, but this should not cause specific antituberculosis therapy to be withheld. Neither test appears to hold marked advantages over conventional chemical analysis of CSF in differentiating TBM from aseptic meningitis.en_ZA
dc.description.versionPublishers'version
dc.format.extentpp.18-20 : ill.
dc.identifier2078-5135 (online)
dc.identifier0256-9574 (print)
dc.identifier.citationDonald, P. R., Malan, Christina. 1985. Cerebrospinal fluid lactate and lactate dehydrogenase levels as diagnostic aids in tuberculous meningitis. South African Medical Journal, 67(1):18-20en_ZA
dc.identifier.urihttp://hdl.handle.net/10019.1/8016
dc.language.isoen_ZAen_ZA
dc.publisherHealth and Medical Publishing Group (HMPG)en_ZA
dc.rights.holderThe authors retain copyright
dc.subjectCerebrospinal fluid -- Diagnostic use -- Tuberculous meningitisen_ZA
dc.subjectTuberculous meningitis -- Diagnosisen_ZA
dc.subjectTuberculous meningitisen_ZA
dc.subjectLactate dehydrogenase -- Diagnostic use -- Tuberculous meningitisen_ZA
dc.subjectDecision makingen_ZA
dc.subjectTuberculous meningitis -- Treatmenten_ZA
dc.subjectTuberculosis -- Therapyen_ZA
dc.titleCerebrospinal fluid lactate and lactate dehydrogenase levels as diagnostic aids in tuberculous meningitisen_ZA
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